PDB entry 6vy4

View 6vy4 on RCSB PDB site
Description: Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-32
Class: viral protein/immune system
Keywords: henipavirus, Hendra virus, receptor binding protein, antibody, antibody-antigen complex, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2020-02-25, released 2020-12-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-30, with a file datestamp of 2020-12-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: receptor binding protein
    Species: Hendra henipavirus [TaxId:63330]
    Database cross-references and differences (RAF-indexed):
    • Uniprot F4YH71 (Start-419)
      • expression tag (420-427)
  • Chain 'B':
    Compound: receptor binding protein
    Species: Hendra henipavirus [TaxId:63330]
    Database cross-references and differences (RAF-indexed):
    • Uniprot F4YH71 (Start-419)
      • expression tag (420-427)
  • Chain 'C':
    Compound: Anti-Hendra receptor binding protein antibody HENV-32 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VY4 (0-End)
    Domains in SCOPe 2.08: d6vy4c_
  • Chain 'D':
    Compound: Anti-Hendra receptor binding protein antibody HENV-32 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VY4 (0-End)
    Domains in SCOPe 2.08: d6vy4d1, d6vy4d2
  • Chain 'H':
    Compound: Anti-Hendra receptor binding protein antibody HENV-32 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VY4 (0-End)
    Domains in SCOPe 2.08: d6vy4h_
  • Chain 'L':
    Compound: Anti-Hendra receptor binding protein antibody HENV-32 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VY4 (0-End)
    Domains in SCOPe 2.08: d6vy4l1, d6vy4l2
  • Heterogens: SO4, NAG, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6vy4C (C:)
qvqlvqsgaevkkpgssvkvsckvsggifnretinwvrqapgqglewmgritpivdvpny
prkfrgrvtitadkststvymelsglrfedtaiyfcarfrghnyfdpwgqgtlvtvssas
fkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >6vy4C (C:)
qvqlvqsgaevkkpgssvkvsckvsggifnretinwvrqapgqglewmgritpivdvpny
prkfrgrvtitadkststvymelsglrfedtaiyfcarfrghnyfdpwgqgtlvtvssas
fkgpsvfplapsalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtv
pssslgtqtyicnvnhkpsntkvdkkv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6vy4D (D:)
syvltqppsvsvapgqtaritcggnniggksvhwyqqkpgqapvlvvyddrdrpsgiper
fsgsnsgdtasltisrvdagdeadyfcqvwdnasdeavfgggtkltvlgqpkanptvtlf
ppsseelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6vy4D (D:)
syvltqppsvsvapgqtaritcggnniggksvhwyqqkpgqapvlvvyddrdrpsgiper
fsgsnsgdtasltisrvdagdeadyfcqvwdnasdeavfgggtkltvlgqpkanptvtlf
ppsseelqankatlvclisdfgavtvawagvettkpskqsnnkyaassylsltpeqwksh
rsyscqvthetvektvap

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6vy4H (H:)
qvqlvqsgaevkkpgssvkvsckvsggifnretinwvrqapgqglewmgritpivdvpny
prkfrgrvtitadkststvymelsglrfedtaiyfcarfrghnyfdpwgqgtlvtvssas
fkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >6vy4H (H:)
qvqlvqsgaevkkpgssvkvsckvsggifnretinwvrqapgqglewmgritpivdvpny
prkfrgrvtitadkststvymelsglrfedtaiyfcarfrghnyfdpwgqgtlvtvssas
fkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkkve

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6vy4L (L:)
syvltqppsvsvapgqtaritcggnniggksvhwyqqkpgqapvlvvyddrdrpsgiper
fsgsnsgdtasltisrvdagdeadyfcqvwdnasdeavfgggtkltvlgqpkanptvtlf
ppsseelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6vy4L (L:)
syvltqppsvsvapgqtaritcggnniggksvhwyqqkpgqapvlvvyddrdrpsgiper
fsgsnsgdtasltisrvdagdeadyfcqvwdnasdeavfgggtkltvlgqpkanptvtlf
ppsseelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvap