PDB entry 6vwh

View 6vwh on RCSB PDB site
Description: leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor ii.
Deposited on 2020-02-19, released 2020-05-13
The last revision was dated 2020-07-22, with a file datestamp of 2020-07-17.
Experiment type: EM
Resolution: 4.26 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: GCN4, AAS3, ARG9, YEL009C
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: GCN4, AAS3, ARG9, YEL009C
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6vwhA (A:)
eicgpgidirndyqqlkrlenctviegylhilliskaedyrsyrfpkltviteylllfrv
agleslgdlfpnltvirgwklfynyalvifemtnlkdiglynlrnitrgairieknadlc
ylstvdwslildavsnnyivgnkppkecgdlcpgtmeekpmcekttinneynyrcwttnr
cqkmcpstcgkractennecchpeclgscsapdndtacvacrhyyyagvcvpacppntyr
fegwrcvdrdfcanilsaessdsegfvihdgecmqecpsgfirngsqsmycipcegpcpk
vceeekktktidsvtsaqmlqgctifkgnllinirrgnniaselenfmglievvtgyvki
rhshalvslsflknlrlilgeeqlegnysfyvldnqnlqqlwdwdhrnltikagkmyfaf
npklcvseiyrmeevtgtkgrqskgdintrnngerascesdvlhftstttsknriiitwh
ryrppdyrdlisftvyykeapfknvteydgqdacgsnswnmvdvdlppnkdvepgillhg
lkpwtqyavyvkavtltmvendhirgakseilyirtnasvpsipldvlsasnsssqlivk
wnppslpngnlsyyivrwqrqpqdgylyrhnycskdkipirkyadgtidieevtenpkte
vcggekgpccacpkteaekqaekeeaeyrkvfenflhnsifvprperkrrdvmqvanttm
ssrsrnttaadtynitdpeeleteypffesrvdnkertvisnlrpftlyridihscnhea
eklgcsasnfvfartmpaegaddipgpvtweprpensiflkwpepenpnglilmyeikyg
sqvedqrecvsrqeyrkyggaklnrlnpgnytariqatslsgngswtdpvffyvqaktgy
enfihrmkqledkveellsknyhlenevarlkklvgerssseqkliseedln

    Sequence, based on observed residues (ATOM records):
    >6vwhA (A:)
nasvpsipldvlsasnsssqlivkwnppslpngnlsyyivrwqrqpqdgylyrhnyceke
eaeyrkvfenflhnsifvpreypffesrvdnkertvisnlrpftlyridihscnheaekl
gcsasnfvfartmpae

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6vwhB (B:)
eicgpgidirndyqqlkrlenctviegylhilliskaedyrsyrfpkltviteylllfrv
agleslgdlfpnltvirgwklfynyalvifemtnlkdiglynlrnitrgairieknadlc
ylstvdwslildavsnnyivgnkppkecgdlcpgtmeekpmcekttinneynyrcwttnr
cqkmcpstcgkractennecchpeclgscsapdndtacvacrhyyyagvcvpacppntyr
fegwrcvdrdfcanilsaessdsegfvihdgecmqecpsgfirngsqsmycipcegpcpk
vceeekktktidsvtsaqmlqgctifkgnllinirrgnniaselenfmglievvtgyvki
rhshalvslsflknlrlilgeeqlegnysfyvldnqnlqqlwdwdhrnltikagkmyfaf
npklcvseiyrmeevtgtkgrqskgdintrnngerascesdvlhftstttsknriiitwh
ryrppdyrdlisftvyykeapfknvteydgqdacgsnswnmvdvdlppnkdvepgillhg
lkpwtqyavyvkavtltmvendhirgakseilyirtnasvpsipldvlsasnsssqlivk
wnppslpngnlsyyivrwqrqpqdgylyrhnycskdkipirkyadgtidieevtenpkte
vcggekgpccacpkteaekqaekeeaeyrkvfenflhnsifvprperkrrdvmqvanttm
ssrsrnttaadtynitdpeeleteypffesrvdnkertvisnlrpftlyridihscnhea
eklgcsasnfvfartmpaegaddipgpvtweprpensiflkwpepenpnglilmyeikyg
sqvedqrecvsrqeyrkyggaklnrlnpgnytariqatslsgngswtdpvffyvqaktgy
enfihrmkqledkveellsknyhlenevarlkklvgerssseqkliseedln

    Sequence, based on observed residues (ATOM records):
    >6vwhB (B:)
eicgpgidirndyqqlkrlenctviegylhilliskarsyrfpkltviteylllfrvagl
eslgdlfpnltvirgwklfynyalvifemtnlkdiglynlrnitrgairieknadlcyls
tvdwslildavsnnyivgnkppkecgdlcpgcekttinneynyrcwttnrcqkmcpstcg
kractennecchpeclgscsapdndtacvacrhyyyagvcvpacppntyrfegwrcvdrd
fcanilsaessdsegfvihdgecmqecpsgfirngsqsmycipcegpcpknasvpsipld
vlsasnsssqlivkwnppslpngnlsyyivrwqrqpqdgylyrhnyceypffesrvdnke
rtvisnlrpftlyridihscnheaeklgcsasnfvfartmpae