PDB entry 6vuy

View 6vuy on RCSB PDB site
Description: crystal structure of eis from mycobacterium tuberculosis in complex with inhibitor sgt358
Deposited on 2020-02-16, released 2020-06-03
The last revision was dated 2020-07-01, with a file datestamp of 2020-06-26.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-acetyltransferase Eis
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: eis, Rv2416c, MTCY253.04
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WFK7 (Start-421)
      • engineered mutation (223)
  • Heterogens: RN4, PEG, DMS, GOL, NA, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6vuyA (A:)
mgsshhhhhhssglvprgshmtvtlcspteddwpgmfllaaasftdfigpesatawrtlv
ptdgavvvrdgagpgsevvgmalymdlrltvpgevvlptaglsfvavapthrrrgllram
caelhrriadsgypvaalhaseggiygrfgygpattlheltvdrrfarfhadapggglgg
ssvrlvrptehrgefeaiyerwrqqvpggllrpqvlwdellaeakaapggdresfallhp
dgyalyrvdrtdlklarvselravtadahcalwraligldsmerisiithpqdplphllt
dtrlarttwrqdglwlrimnvpaaleargyahevgefstvlevsdggrfalkigdgrarc
tptdaaaeiemdrdvlgslylgahrastlaaanrlrtkdsqllrrldaafasdvpvqtaf
ef

    Sequence, based on observed residues (ATOM records):
    >6vuyA (A:)
vtlcspteddwpgmfllaaasftdfigpesatawrtlvptdgavvvrdgsevvgmalymd
lrltvpgevvlptaglsfvavapthrrrgllramcaelhrriadsgypvaalhaseggiy
grfgygpattlheltvdrrfarfhadapggglggssvrlvrptehrgefeaiyerwrqqv
pggllrpqvlwdellaeakaapggdresfallhpdgyalyrvdrtdlklarvselravta
dahcalwraligldsmerisiithpqdplphlltdtrlarttwrqdglwlrimnvpaale
argyahevgefstvlevsdggrfalkigdgrarctptdaaaeiemdrdvlgslylgahra
stlaaanrlrtkdsqllrrldaafasdvpvqtafef