PDB entry 6vrg

View 6vrg on RCSB PDB site
Description: Structure of HIV-1 integrase with native amino-terminal sequence
Class: viral protein
Keywords: Integrase, Zinc Ion Binding, Nucleic Acid Binding, DNA Integration, VIRAL PROTEIN
Deposited on 2020-02-07, released 2020-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-16, with a file datestamp of 2020-09-11.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot F2WR39 (0-End)
      • engineered mutation (130)
      • engineered mutation (184)
    Domains in SCOPe 2.08: d6vrga1, d6vrga2
  • Chain 'B':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot F2WR39 (0-End)
      • engineered mutation (130)
      • engineered mutation (184)
    Domains in SCOPe 2.08: d6vrgb1, d6vrgb2
  • Chain 'C':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot F2WR39 (0-End)
      • engineered mutation (130)
      • engineered mutation (184)
    Domains in SCOPe 2.08: d6vrgc1, d6vrgc2
  • Chain 'D':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot F2WR39 (0-End)
      • engineered mutation (130)
      • engineered mutation (184)
    Domains in SCOPe 2.08: d6vrgd1, d6vrgd2
  • Heterogens: ZN, K, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vrgA (A:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlkgeamhgqvdcspgi
wqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsn
ftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktavqmav
fihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6vrgA (A:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlcspgiwqldcthleg
kvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsnftsttvkaac
dwagikqegviesmnkelkkiigqvrdqaehlktavqmavfihnkkrkggiggysageri
vdiiatdiqtk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6vrgB (B:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlkgeamhgqvdcspgi
wqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsn
ftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktavqmav
fihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6vrgB (B:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlcspgiwqldcthleg
kvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsnftsttvkaac
dwagikqeviesmnkelkkiigqvrdqaehlktavqmavfihnkkrkggiggysageriv
diiatdiqt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6vrgC (C:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlkgeamhgqvdcspgi
wqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsn
ftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktavqmav
fihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6vrgC (C:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlcspgiwqldcthleg
kvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsnftsttvkaac
dwagikqesmnkelkkiigqvrdqaehlktavqmavfihnkkrkggiggysagerivdii
atdiqt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6vrgD (D:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlkgeamhgqvdcspgi
wqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsn
ftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktavqmav
fihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6vrgD (D:)
fldgidkaqeehekyhsnwramasdfnlppvvakeivascdkcqlcspgiwqldcthleg
kvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtdngsnftsttvkaac
dwagikqeviesmnkelkkiigqvrdqaehlktavqmavfihnkkrkggiggysageriv
diiatdiq