PDB entry 6vr6

View 6vr6 on RCSB PDB site
Description: Structure of ALDH9A1 complexed with NAD+ in space group P1
Class: oxidoreductase
Keywords: oxidoreductase, aldehyde dehydrogenase, nad
Deposited on 2020-02-06, released 2020-08-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6a_
  • Chain 'B':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6b_
  • Chain 'C':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6c_
  • Chain 'D':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6d_
  • Chain 'E':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6e_
  • Chain 'F':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6f_
  • Chain 'G':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6g_
  • Chain 'H':
    Compound: 4-trimethylaminobutyraldehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH9A1, ALDH4, ALDH7, ALDH9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vr6h_
  • Heterogens: NAD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vr6A (A:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

    Sequence, based on observed residues (ATOM records): (download) 
    >6vr6A (A:)
tgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaaf
kiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyyag
laasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkps
pftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkime
msakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeild
kfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyvp
edpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaag
vftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlkt
vcvemgdvesaf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6vr6B (B:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

    Sequence, based on observed residues (ATOM records): (download) 
    >6vr6B (B:)
tgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaaf
kiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyyag
laasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkps
pftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkime
msakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeild
kfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyvp
edpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaag
vftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlkt
vcvemgdvesaf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6vr6C (C:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

    Sequence, based on observed residues (ATOM records): (download) 
    >6vr6C (C:)
tgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaaf
kiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyyag
laasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkps
pftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkime
msakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeild
kfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyvp
edpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaag
vftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlkt
vcvemgdvesaf

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6vr6D (D:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6vr6E (E:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6vr6F (F:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

    Sequence, based on observed residues (ATOM records): (download) 
    >6vr6F (F:)
tgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaaf
kiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyyag
laasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkps
pftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkime
msakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeild
kfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyvp
edpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaag
vftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlkt
vcvemgdvesaf

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6vr6G (G:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6vr6H (H:)
stgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaa
fkiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyya
glaasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkp
spftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkim
emsakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeil
dkfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyv
pedpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaa
gvftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlk
tvcvemgdvesaf

    Sequence, based on observed residues (ATOM records): (download) 
    >6vr6H (H:)
tgtfvvsqplnyrggarvepadasgtekafepatgrviatftcsgekevnlavqnakaaf
kiwsqksgmercrilleaariireredeiatmecinngksifearldidiswqcleyyag
laasmagehiqlpggsfgytrreplgvcvgigawnypfqiaswksapalacgnamvfkps
pftpvsalllaeiyseagvppglfnvvqggaatgqflcqhpdvakvsftgsvptgmkime
msakgikpvtlelggkspliifsdcdmnnavkgalmanfltqgqvccngtrvfvqkeild
kfteevvkqtqrikigdplledtrmgplinrphlervlgfvkvakeqgakvlcggdiyvp
edpklkdgyymrpcvltncrddmtcvkeeifgpvmsilsfdteaevlerandttfglaag
vftrdiqrahrvvaelqagtcfinnynvspvelpfggykksgfgrengrvtieyysqlkt
vcvemgdvesaf