PDB entry 6vqs

View 6vqs on RCSB PDB site
Description: HIV Integrase Core domain (IN) in complex with [5-(3-fluorophenyl)-1-benzofuran-3-yl]acetic acid
Class: transferase
Keywords: Virus, Inhibitor, Complex, HIV Integrase, TRANSFERASE
Deposited on 2020-02-05, released 2021-02-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-10, with a file datestamp of 2021-02-05.
Experiment type: XRAY
Resolution: 2.38 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q76353
      • conflict (81)
      • conflict (135)
    Domains in SCOPe 2.08: d6vqsa_
  • Heterogens: R7J, SO4, IOD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vqsA (A:)
mhgevdsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacewagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnkkrkggiggysagerivdiiatdietke

    Sequence, based on observed residues (ATOM records): (download) 
    >6vqsA (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacewagikqefgnkelkkiigqvrdqaehlktavqmavfihnkkrkgg
iggysagerivdiiat