PDB entry 6vqm

View 6vqm on RCSB PDB site
Description: Crystal Structure Analysis of human ACK1
Class: transferase
Keywords: Non-receptor tyrosine-protein and serine/threonine-protein kinase, Kinase inhibitor, TRANSFERASE
Deposited on 2020-02-05, released 2021-02-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-10, with a file datestamp of 2021-02-05.
Experiment type: XRAY
Resolution: 2.87 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Activated CDC42 kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TNK2, ACK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6vqma_
  • Chain 'B':
    Compound: Activated CDC42 kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TNK2, ACK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6vqmb_
  • Heterogens: R7P, SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6vqmA (A:)
    gsagegplqsltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvls
    qpeamddfirevnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfll
    gtlsryavqvaegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvm
    qehrkvpfawcapeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidke
    gerlprpedcpqdiynvmvqcwahkpedrptfvalrdflleaqptdmra
    

    Sequence, based on observed residues (ATOM records): (download)
    >6vqmA (A:)
    ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclpeamddfirevnamhs
    ldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqvaegmgyl
    eskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfawcapeslk
    trtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqdiynv
    mvqcwahkpedrptfvalrdflleaqp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6vqmB (B:)
    gsagegplqsltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvls
    qpeamddfirevnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfll
    gtlsryavqvaegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvm
    qehrkvpfawcapeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidke
    gerlprpedcpqdiynvmvqcwahkpedrptfvalrdflleaqptdmra
    

    Sequence, based on observed residues (ATOM records): (download)
    >6vqmB (B:)
    ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclamddfirevnamhsld
    hrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqvaegmgyles
    krfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfawcapeslktr
    tfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqdiynvmv
    qcwahkpedrptfvalrdflleaqptd