PDB entry 6vnq

View 6vnq on RCSB PDB site
Description: crystal structure of danio rerio histone deacetylase 10 in complex with bishydroxamic acid based inhibitor
Deposited on 2020-01-29, released 2020-05-13
The last revision was dated 2020-07-15, with a file datestamp of 2020-07-10.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polyamine deacetylase HDAC10
    Species: Danio rerio [TaxId:7955]
    Gene: hdac10
    Database cross-references and differences (RAF-indexed):
    • Uniprot F1QCV2 (1-674)
      • expression tag (0)
      • engineered mutation (23)
      • engineered mutation (93)
      • conflict (153)
      • conflict (547)
      • conflict (585)
      • conflict (592)
      • conflict (595)
      • conflict (612)
      • conflict (645)
      • expression tag (675)
  • Heterogens: R5G, EDO, ZN, K, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6vnqA (A:)
aasgsalifdeemsrykllwtdpeceievperltvsyealrthglaqrckavpvrqateq
eillahseeyleavkqtpgmnveelmafskkynavyfhqniyhcaklaagatlqlvdsvm
krevrngmalvrppghhsqrsaangfcvfnnvafaalyakknynlnrilivdwdvhhgqg
iqycfeedpsvlyfswhryehqsfwpnlpesdyssvgkgkgsgfninlpwnkvgmtnsdy
laaffhvllpvayefdpelvivsagfdsaigdpegemcalpeifahlthllmplaagkmc
vvleggynltslgqsvcqtvhsllgdptprisglgtacdsalesiqnvrnvqssywssfk
hlaqsetnpkrprldatnggpkessepasesnpkktaqdivwpeplkrmpasvrtvvvpp
pgveltlpkncqhsgdisestakevqrirdkhfhdltdqnilrslgniisvldrmmrsde
vcngcvvvsdlsvsvqcalqhaltepaervlvvyvgdgelpvktndgkvflvqictkete
dkcvnrltlclregesltagfmqallglilpvayefnpalvlgiveetaaktrlmrvwgh
mtcliqglargrmltllqgydkdlleltvsalsgasisplgplrapkpedvemmekqrqr
lqerwgllrctvsesw

    Sequence, based on observed residues (ATOM records):
    >6vnqA (A:)
aasgsalifdeemsrykllwtdpeceievperltvsyealrthglaqrckavpvrqateq
eillahseeyleavkqtpgmnveelmafskkynavyfhqniyhcaklaagatlqlvdsvm
krevrngmalvrppghhsqrsaangfcvfnnvafaalyakknynlnrilivdwdvhhgqg
iqycfeedpsvlyfswhryehqsfwpnlpesdyssvgkgkgsgfninlpwnkvgmtnsdy
laaffhvllpvayefdpelvivsagfdsaigdpegemcalpeifahlthllmplaagkmc
vvleggynltslgqsvcqtvhsllgdptprisglgtacdsalesiqnvrnvqssywssfk
hlaqsedivwpeplkrmpasvrtvvvpppgveltlpkncqhsisestakevqrirdkhfh
dltdqnilrslgniisvldrmmrsdevcngcvvvsdlsvsvqcalqhaltepaervlvvy
vgdgelpvktndgkvflvqictketedkcvnrltlclregesltagfmqallglilpvay
efnpalvlgiveetrlmrvwghmtcliqglargrmltllqgydkdlleltvsalsgasis
plgplrapkpedvemmekqrqrlqerwgllrctvsesw