PDB entry 6vm9

View 6vm9 on RCSB PDB site
Description: t4h2 t cell receptor bound to hla-a2 presenting gp100t2m peptide (imdqvpfsv)
Deposited on 2020-01-27, released 2021-01-20
The last revision was dated 2021-01-27, with a file datestamp of 2021-01-22.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MHC class I antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
  • Chain 'C':
    Compound: Melanocyte protein PMEL
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40967 (0-8)
      • engineered mutation (1)
  • Chain 'D':
    Compound: T4H2 T cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV12-2, TRAC
    Database cross-references and differences (RAF-indexed):
    • PDB 6VM9
  • Chain 'E':
    Compound: T4H2 T cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV19, TRBC2
    Database cross-references and differences (RAF-indexed):
    • PDB 6VM9 (Start-240)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6vm9A (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwe

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6vm9B (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6vm9C (C:)
imdqvpfsv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6vm9D (D:)
mqkeveqnsgplsvpegaiaslnctysdrgsqsffwyrqysgkspelimsiysngdkedg
rftaqlnkasqyvsllirdsqpsdsatylcavnallgnqfyfgtgtsltvipniqnpdpa
vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnk
sdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records):
    >6vm9D (D:)
qkeveqnsgplsvpegaiaslnctysdrgsqsffwyrqysgkspelimsiysngdkedgr
ftaqlnkasqyvsllirdsqpsdsatylcavnallgnqfyfgtgtsltvipniqnpdpav
yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
dfacanafnnsiipedtffps

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6vm9E (E:)
mgitqspkylfrkegqnvtlsceqnlnhdamywyrqdpgqglrliyysqivndfqkgdia
egysvsrekkesfpltvtsaqknptafylcassmggtyeqyfgpgtrltvtedlknvfpp
evavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpal
ndsryalssrlrvsatfwqdprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgra
d

    Sequence, based on observed residues (ATOM records):
    >6vm9E (E:)
gitqspkylfrkegqnvtlsceqnlnhdamywyrqdpgqglrliyysqivndfqkgdiae
gysvsrekkesfpltvtsaqknptafylcassmggtyeqyfgpgtrltvtedlknvfppe
vavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpaln
dsryalssrlrvsatfwqdprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad