PDB entry 6vlm

View 6vlm on RCSB PDB site
Description: Core Catalytic Domain of HIV Integrase in complex with virtual screening hit
Class: transferase/transferase inhibitor
Keywords: Inhibitor, Hydrolase, Viral Protein, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2020-01-24, released 2020-05-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-05-13, with a file datestamp of 2020-05-08.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0U2U525
      • conflict (103)
      • conflict (149)
    Domains in SCOPe 2.07: d6vlma_
  • Chain 'B':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0U2U525
      • conflict (103)
      • conflict (149)
    Domains in SCOPe 2.07: d6vlmb_
  • Heterogens: R2D, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vlmA (A:)
mahhhhhhlvprgsmhgqvdsspgiwqldcthlegkvilvavhvasgyieaevipaetgq
etayfllklagrwpvktihtdngsnftsttvkaacwwagikqedgipynpqsqgvvesmn
kelkkiigqvrdqaehlktavqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6vlmA (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktihtd
ngsnftsttvkaacwwagikqedgipynpqsqgvvesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkgysagerivdiiatdiqt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6vlmB (B:)
mahhhhhhlvprgsmhgqvdsspgiwqldcthlegkvilvavhvasgyieaevipaetgq
etayfllklagrwpvktihtdngsnftsttvkaacwwagikqedgipynpqsqgvvesmn
kelkkiigqvrdqaehlktavqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6vlmB (B:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktihtd
ngsnftsttvkaacwwagikqedgipynpqsqgvvesmnkelkkiigqvrdqaehlktav
qmavfihnhkrgysagerivdiiatdiqt