PDB entry 6vjc

View 6vjc on RCSB PDB site
Description: LmFPPS mutant T164Y in complex with 476A, IPP & Ca
Class: transferase
Keywords: FPPS, farnesyl diphosphate synthase, Isoprenoid, TRANSFERASE
Deposited on 2020-01-15, released 2020-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: farnesyl pyrophosphate synthase
    Species: Leishmania major [TaxId:5664]
    Gene: FPPS, LMJF_22_1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4QBL1 (1-361)
      • expression tag (0)
      • engineered mutation (163)
    Domains in SCOPe 2.08: d6vjca1, d6vjca2
  • Chain 'B':
    Compound: farnesyl pyrophosphate synthase
    Species: Leishmania major [TaxId:5664]
    Gene: FPPS, LMJF_22_1360
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4QBL1 (1-361)
      • expression tag (0)
      • engineered mutation (163)
    Domains in SCOPe 2.08: d6vjcb1, d6vjcb2
  • Heterogens: 476, IPR, CA, ACT, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6vjcA (A:)
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdlttyigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
qk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6vjcB (B:)
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdlttyigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
qk