PDB entry 6vi4

View 6vi4 on RCSB PDB site
Description: nanobody-enabled monitoring of kappa opioid receptor states
Deposited on 2020-01-11, released 2020-03-18
The last revision was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kappa opioid receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: OPRK1, OPRK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41145
      • engineered mutation (83)
  • Chain 'B':
    Compound: Kappa opioid receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: OPRK1, OPRK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41145
      • engineered mutation (83)
  • Chain 'C':
    Compound: Nanobody 6
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VI4
  • Chain 'D':
    Compound: Nanobody 6
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VI4
  • Heterogens: JDC, CLR

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6vi4A (A:)
gsispaipviitavysvvfvvglvgnslvmfviirytkmktatniyifnlaladalvttt
mpfqstvylmnswpfgdvlckivlsidyynmftsiftltmmsvdryiavchpvkaldfrt
plkakiiniciwllsssvgisaivlggtkvredvdviecslqfpdddyswwdlfmkicvf
ifafvipvliiivcytlmilrlksvrllsgsrekdrnlrritrlvlvvvavfvvcwtpih
ifilvealgstshstaalssyyfcialgytnsslnpilyafldenfkrcfrdfcfplkmr
merqsts

    Sequence, based on observed residues (ATOM records):
    >6vi4A (A:)
viitavysvvfvvglvgnslvmfviirytkmktatniyifnlaladalvtttmpfqstvy
lmnswpfgdvlckivlsidyynmftsiftltmmsvdryiavchpvkaldfrtplkakiin
iciwllsssvgisaivlggtkvredvdviecslqfpdddyswwdlfmkicvfifafvipv
liiivcytlmilrlksvrllsgsrekdrnlrritrlvlvvvavfvvcwtpihifilveal
gaalssyyfcialgytnsslnpilyafldenfkrcfrdfcfpl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6vi4B (B:)
gsispaipviitavysvvfvvglvgnslvmfviirytkmktatniyifnlaladalvttt
mpfqstvylmnswpfgdvlckivlsidyynmftsiftltmmsvdryiavchpvkaldfrt
plkakiiniciwllsssvgisaivlggtkvredvdviecslqfpdddyswwdlfmkicvf
ifafvipvliiivcytlmilrlksvrllsgsrekdrnlrritrlvlvvvavfvvcwtpih
ifilvealgstshstaalssyyfcialgytnsslnpilyafldenfkrcfrdfcfplkmr
merqsts

    Sequence, based on observed residues (ATOM records):
    >6vi4B (B:)
iitavysvvfvvglvgnslvmfviirytkmktatniyifnlaladalvtttmpfqstvyl
mnswpfgdvlckivlsidyynmftsiftltmmsvdryiavchpvkaldfrtplkakiini
ciwllsssvgisaivlggtkvredvdviecslqdyswwdlfmkicvfifafvipvliiiv
cytlmilrlksvrllsgsrekdrnlrritrlvlvvvavfvvcwtpihifilvealgalss
yyfcialgytnsslnpilyafldenfkrcfrdfcfp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6vi4C (C:)
maqvqlqesggglvqageslrlscaasgtifrlydmgwyrrvsgnqrelvasitsggstk
ygdsvkgrftisrdnakntvylqmsslkpedtavyycnaeyrtgiweelldgwgqgtqvt
vsshhhhhhepea

    Sequence, based on observed residues (ATOM records):
    >6vi4C (C:)
qvqlqesggglvqageslrlscaasgtifrlydmgwyrgnqrelvasitsggstkygdsv
kgrftisrdnakntvylqmsslkpedtavyycnaeyrtgiweelldgwgqgtqvtvss

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6vi4D (D:)
maqvqlqesggglvqageslrlscaasgtifrlydmgwyrrvsgnqrelvasitsggstk
ygdsvkgrftisrdnakntvylqmsslkpedtavyycnaeyrtgiweelldgwgqgtqvt
vsshhhhhhepea

    Sequence, based on observed residues (ATOM records):
    >6vi4D (D:)
qvqlqesggglvqageslrlscaasgtifrlydmgwyrrelvasitsggstkygdsvkgr
ftisrdnakntvylqmsslkpedtavyycnaeyrtgiweelldgwgqgtqvtvsshh