PDB entry 6vh2

View 6vh2 on RCSB PDB site
Description: 2.26 A resolution structure of MERS 3CL protease in complex with inhibitor 7i
Class: Hydrolase/Hydrolase Inhibitor
Keywords: PROTEASE, MERS 3CL protease Inhhibitors, HYDROLASE, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2020-01-09, released 2020-08-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Orf1a protein
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Gene: ORF1a
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vh2a1, d6vh2a2
  • Chain 'B':
    Compound: Orf1a protein
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Gene: ORF1a
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6vh2b1, d6vh2b2
  • Heterogens: QZ4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vh2A (A:)
mhhhhhhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpn
ydallismtnhsfsvqkhigapanlrvvghamqgtllkltvdvanpstpaytfttvkpga
afsvlacyngrptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelang
thtgsafdgtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsf
newalanqftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftp
edvnmqimgvvmq

    Sequence, based on observed residues (ATOM records): (download) 
    >6vh2A (A:)
hhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpnydall
ismtnhsfsvqkhianlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlacy
ngrptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelangthtgsafd
gtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsfnewalanq
ftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftpedvnmqi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6vh2B (B:)
mhhhhhhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpn
ydallismtnhsfsvqkhigapanlrvvghamqgtllkltvdvanpstpaytfttvkpga
afsvlacyngrptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelang
thtgsafdgtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsf
newalanqftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftp
edvnmqimgvvmq

    Sequence, based on observed residues (ATOM records): (download) 
    >6vh2B (B:)
hhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpnydall
ismtnhsfsvqkhianlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlacy
ngrptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelangthtgsafd
gtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsfnewalanq
ftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftpedvnmqim
gv