PDB entry 6vbq

View 6vbq on RCSB PDB site
Description: crystal structure of anti-hiv-1 antibody dh822 bound to gp120 v2 peptide
Deposited on 2019-12-19, released 2020-02-12
The last revision was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 2.12 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DH822 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ (0-End)
  • Chain 'B':
    Compound: DH822 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ
  • Chain 'C':
    Compound: DH822 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ (0-End)
  • Chain 'D':
    Compound: DH822 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ
  • Chain 'E':
    Compound: DH822 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ (0-End)
  • Chain 'F':
    Compound: DH822 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ
  • Chain 'H':
    Compound: DH822 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ (0-End)
  • Chain 'I':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: DH822 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBQ
  • Chain 'P':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6vbqA (A:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbqA (A:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6vbqB (B:)
syeltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiper
fsgsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records):
    >6vbqB (B:)
eltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiperfs
gsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlfpp
sseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsl
tpeqwkshrsyscqvthegstvektvap

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6vbqC (C:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbqC (C:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapsssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6vbqD (D:)
syeltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiper
fsgsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records):
    >6vbqD (D:)
eltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiperfs
gsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlfpp
sseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsl
tpeqwkshrsyscqvthegstvektvap

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6vbqE (E:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbqE (E:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6vbqF (F:)
syeltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiper
fsgsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records):
    >6vbqF (F:)
eltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiperfs
gsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlfpp
sseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsl
tpeqwkshrsyscqvthegstvektvap

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6vbqH (H:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbqH (H:)
qvqlvqsgaevkkpgasvklsckasgytftdyyihwvrqapgqglewmgiinprrdttty
aqkfqgrvtmtrdtstntvymelsslrsddtavyfcaknvgfcnsdscyvgmdvwgpgtt
vtissastkgpsvfplapsssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6vbqI (I:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbqI (I:)
kkqkvhalfykldiv

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6vbqJ (J:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbqJ (J:)
kkqkvhalfykldiv

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6vbqK (K:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbqK (K:)
kkqkvhalfykld

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6vbqL (L:)
syeltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiper
fsgsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records):
    >6vbqL (L:)
eltqppsmsvspgqtaritcsadvlpkqyaywyqqkpgqapllliykdterpsgiperfs
gsssgttvtltisgvqaedeadyycqstdssdiylvfgggtkltvlgqpkaapsvtlfpp
sseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsl
tpeqwkshrsyscqvthegstvektvap

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6vbqP (P:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbqP (P:)
kkqkvhalfykldiv