PDB entry 6vbp

View 6vbp on RCSB PDB site
Description: crystal structure of anti-hiv-1 antibody dh815 bound to gp120 v2 peptide
Deposited on 2019-12-19, released 2020-02-12
The last revision was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DH815 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Chain 'B':
    Compound: DH815 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Chain 'C':
    Compound: DH815 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Chain 'D':
    Compound: DH815 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Chain 'E':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: DH815 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Chain 'I':
    Compound: DH815 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Chain 'J':
    Compound: DH815 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Chain 'K':
    Compound: envelope glycoprotein gp160
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: DH815 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6VBP (0-End)
  • Heterogens: CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6vbpA (A:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbpA (A:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6vbpB (B:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6vbpB (B:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6vbpC (C:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbpC (C:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6vbpD (D:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6vbpD (D:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6vbpE (E:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbpE (E:)
vhalfykldivpi

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6vbpF (F:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbpF (F:)
vhalfykldivpie

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6vbpG (G:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbpG (G:)
kvhalfykldivpi

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6vbpH (H:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbpH (H:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6vbpI (I:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6vbpI (I:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6vbpJ (J:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdk

    Sequence, based on observed residues (ATOM records):
    >6vbpJ (J:)
evqlvqsgaevkkpgeslrisckgsgynftnywigwvrqvpgkgpewmgliypsdsdtry
npslqghvtisadkslttaylrwsslrasdsatyycvtsgiygyldywgrgtqvivssas
tkgpsvfplapsstaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkrvepks

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6vbpK (K:)
lrdkkqkvhalfykldivpied

    Sequence, based on observed residues (ATOM records):
    >6vbpK (K:)
vhalfykldivp

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6vbpL (L:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6vbpL (L:)
divmtqspdslavslgeratinckssqsvfhssnnknylawyqqkpgqspkllihwasar
esgvperisgsgsgtdftltisslqaedvavyycqqyystpltfgggtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrg