PDB entry 6vbm

View 6vbm on RCSB PDB site
Description: Crystal structure of a S310A mutant of PBP2 from Neisseria gonorrhoeae
Class: hydrolase
Keywords: penicillin-binding protein, transpeptidase domain, antibiotic resistance, hydrolase
Deposited on 2019-12-19, released 2020-04-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-15, with a file datestamp of 2020-04-10.
Experiment type: XRAY
Resolution: 1.71 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable peptidoglycan D,D-transpeptidase PenA
    Species: NEISSERIA GONORRHOEAE [TaxId:485]
    Gene: penA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08149 (5-End)
      • expression tag (4)
      • conflict (51)
      • engineered mutation (64)
    Domains in SCOPe 2.08: d6vbma1, d6vbma2
  • Chain 'B':
    Compound: Probable peptidoglycan D,D-transpeptidase PenA
    Species: NEISSERIA GONORRHOEAE [TaxId:485]
    Gene: penA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08149 (5-328)
      • expression tag (4)
      • conflict (51)
      • engineered mutation (64)
    Domains in SCOPe 2.08: d6vbmb1, d6vbmb2
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vbmA (A:)
gsggalsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdm
iepgaaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnv
gtsklsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglq
lsllqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgt
agavdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyg
gvvagppfkkimggslnilgisptkplta

    Sequence, based on observed residues (ATOM records): (download) 
    >6vbmA (A:)
alsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdmiepg
aaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgtsk
lsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqlsll
qlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtagav
dgfdvgaktgtarkkhvatfigfapaknprvivavtideptahgyyggvvagppfkkimg
gslnilgisptkplt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6vbmB (B:)
gsggalsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdm
iepgaaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnv
gtsklsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglq
lsllqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgt
agavdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyg
gvvagppfkkimggslnilgisptkplta

    Sequence, based on observed residues (ATOM records): (download) 
    >6vbmB (B:)
alsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdmiepg
aaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgtsk
lsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqlsll
qlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtagav
dgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyggvva
gppfkkimggslnilgisptkplta