PDB entry 6vbd

View 6vbd on RCSB PDB site
Description: Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 acylated by ceftriaxone
Class: hydrolase/antibiotic
Keywords: PENICILLIN-BINDING PROTEIN, ACYLATION, ANTIBIOTIC RESISTANCE, HYDROLASE, HYDROLASE-ANTIBIOTIC complex
Deposited on 2019-12-18, released 2020-04-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-15, with a file datestamp of 2020-04-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable peptidoglycan D,D-transpeptidase PenA
    Species: NEISSERIA GONORRHOEAE [TaxId:485]
    Gene: penA
    Database cross-references and differences (RAF-indexed):
    • Uniprot F2Z7K9 (5-End)
      • expression tag (4)
      • conflict (51)
    Domains in SCOPe 2.08: d6vbda1, d6vbda2
  • Heterogens: CEF, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6vbdA (A:)
gsggalsldqriqtlayeelnkaveyhqakagtvvvldartgeilalvntpgrnravtdm
iepgsvmkpfpiakaldsgkvdttdtfntlpykigpatvqdthvyptldvrgimqkssnv
gtsklsamftpkemydfyhdlgvgvrmhsgfpgesagvlrnwrkwrpieqatmsfgyglq
lsllqlaraytvlthdgellpvsfekqavapkgkrvikastakkvrelmvsvteaggsgi
agavdgfdvgaktgtarklvngryvdykhvatfigfapaknprvivavtideptangyys
gvvtgpvfkqvmggslnilgvsptkpltnv

    Sequence, based on observed residues (ATOM records): (download) 
    >6vbdA (A:)
alsldqriqtlayeelnkaveyhqakagtvvvldartgeilalvntpgrnravtdmiepg
svmkpfpiakaldsgkvdttdtfntlpykigpatvqdthvyptldvrgimqkssnvgtsk
lsamftpkemydfyhdlgvgvrmhsgfpgesagvlrnwrkwrpieqatmsfgyglqlsll
qlaraytvlthdgellpvsfekqavapkgkrvikastakkvrelmvsvteaggsgiagav
dgfdvgaktgtarklvngryvdykhvatfigfapaknprvivavtideptangyysgvvt
gpvfkqvmggslnilgvsptkplt