PDB entry 6v9x

View 6v9x on RCSB PDB site
Description: structure of trpa1 modified by iodoacetamide, pmal-c8
Deposited on 2019-12-16, released 2020-05-06
The last revision was dated 2020-09-16, with a file datestamp of 2020-09-11.
Experiment type: EM
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transient receptor potential cation channel subfamily A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPA1, ANKTM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75762
      • engineered mutation (965)
  • Chain 'B':
    Compound: Transient receptor potential cation channel subfamily A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPA1, ANKTM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75762
      • engineered mutation (965)
  • Chain 'C':
    Compound: Transient receptor potential cation channel subfamily A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPA1, ANKTM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75762
      • engineered mutation (965)
  • Chain 'D':
    Compound: Transient receptor potential cation channel subfamily A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPA1, ANKTM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75762
      • engineered mutation (965)
  • Heterogens: YCM

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6v9xA (A:)
mkrslrkmwrpgekkepqgvvyedvpddtedfkeslkvvfegsayglqnfnkqkklkrcd
dmdtfflhyaaaegqielmekitrdsslevlhemddygntplhcaveknqiesvkfllsr
ganpnlrnfnmmaplhiavqgmnnevmkvllehrtidvnlegengntaviiacttnnsea
lqillkkgakpcksnkwgcfpihqaafsgskecmeiilrfgeehgysrqlhinfmnngka
tplhlavqngdlemikmcldngaqidpvekgrctaihfaatqgateivklmissysgsvd
ivnttdgchetmlhraslfdhheladylisvgadinkidsegrsplilatasaswnivnl
llskgaqvdikdnfgrnflhltvqqpyglknlrpefmqmqqikelvmdedndgctplhya
crqggpgsvnnllgfnvsihskskdkksplhfaasygrintcqrllqdisdtrllnegdl
hgmtplhlaaknghdkvvqlllkkgalflsdhngwtalhhasmggytqtmkvildtnlkc
tdrldedgntalhfaareghakavalllshnadivlnkqqasflhlalhnkrkevvltii
rskrwdeclkifshnspgnkcpitemieylpecmkvlldfcmlhstedkscrdyyieynf
kylqcpleftkktptqdviyepltalnamvqnnriellnhpvckeyllmkwlaygfrahm
mnlgsyclglipmtilvvnikpgmafnstgiinetsdhseildttnsyliktcmilvfls
sifgyckeagqifqqkrnyfmdisnvlewiiyttgiifvlplfveipahlqwqcgaiavy
fywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfss
pllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlligla
vgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkprsggmlfhif
cflfctgeirqeipnadkslemeilkqkyrlkdltfllekqhelikliiqkmeiiseted
ddshcsfqdrfkkeqmeqrnsrwntvlravkakthhlep

    Sequence, based on observed residues (ATOM records):
    >6v9xA (A:)
ksplhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkga
lflsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakaval
llshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitem
ieylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltal
namvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmas
yliktcmilvflssifgyckeagdisnvlewiiyttgiifvlplfveipahlqwqcgaia
vyfywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpf
sspllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnllig
lavgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6v9xB (B:)
mkrslrkmwrpgekkepqgvvyedvpddtedfkeslkvvfegsayglqnfnkqkklkrcd
dmdtfflhyaaaegqielmekitrdsslevlhemddygntplhcaveknqiesvkfllsr
ganpnlrnfnmmaplhiavqgmnnevmkvllehrtidvnlegengntaviiacttnnsea
lqillkkgakpcksnkwgcfpihqaafsgskecmeiilrfgeehgysrqlhinfmnngka
tplhlavqngdlemikmcldngaqidpvekgrctaihfaatqgateivklmissysgsvd
ivnttdgchetmlhraslfdhheladylisvgadinkidsegrsplilatasaswnivnl
llskgaqvdikdnfgrnflhltvqqpyglknlrpefmqmqqikelvmdedndgctplhya
crqggpgsvnnllgfnvsihskskdkksplhfaasygrintcqrllqdisdtrllnegdl
hgmtplhlaaknghdkvvqlllkkgalflsdhngwtalhhasmggytqtmkvildtnlkc
tdrldedgntalhfaareghakavalllshnadivlnkqqasflhlalhnkrkevvltii
rskrwdeclkifshnspgnkcpitemieylpecmkvlldfcmlhstedkscrdyyieynf
kylqcpleftkktptqdviyepltalnamvqnnriellnhpvckeyllmkwlaygfrahm
mnlgsyclglipmtilvvnikpgmafnstgiinetsdhseildttnsyliktcmilvfls
sifgyckeagqifqqkrnyfmdisnvlewiiyttgiifvlplfveipahlqwqcgaiavy
fywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfss
pllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlligla
vgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkprsggmlfhif
cflfctgeirqeipnadkslemeilkqkyrlkdltfllekqhelikliiqkmeiiseted
ddshcsfqdrfkkeqmeqrnsrwntvlravkakthhlep

    Sequence, based on observed residues (ATOM records):
    >6v9xB (B:)
ksplhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkga
lflsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakaval
llshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitem
ieylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltal
namvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmas
yliktcmilvflssifgyckeagdisnvlewiiyttgiifvlplfveipahlqwqcgaia
vyfywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpf
sspllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnllig
lavgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6v9xC (C:)
mkrslrkmwrpgekkepqgvvyedvpddtedfkeslkvvfegsayglqnfnkqkklkrcd
dmdtfflhyaaaegqielmekitrdsslevlhemddygntplhcaveknqiesvkfllsr
ganpnlrnfnmmaplhiavqgmnnevmkvllehrtidvnlegengntaviiacttnnsea
lqillkkgakpcksnkwgcfpihqaafsgskecmeiilrfgeehgysrqlhinfmnngka
tplhlavqngdlemikmcldngaqidpvekgrctaihfaatqgateivklmissysgsvd
ivnttdgchetmlhraslfdhheladylisvgadinkidsegrsplilatasaswnivnl
llskgaqvdikdnfgrnflhltvqqpyglknlrpefmqmqqikelvmdedndgctplhya
crqggpgsvnnllgfnvsihskskdkksplhfaasygrintcqrllqdisdtrllnegdl
hgmtplhlaaknghdkvvqlllkkgalflsdhngwtalhhasmggytqtmkvildtnlkc
tdrldedgntalhfaareghakavalllshnadivlnkqqasflhlalhnkrkevvltii
rskrwdeclkifshnspgnkcpitemieylpecmkvlldfcmlhstedkscrdyyieynf
kylqcpleftkktptqdviyepltalnamvqnnriellnhpvckeyllmkwlaygfrahm
mnlgsyclglipmtilvvnikpgmafnstgiinetsdhseildttnsyliktcmilvfls
sifgyckeagqifqqkrnyfmdisnvlewiiyttgiifvlplfveipahlqwqcgaiavy
fywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfss
pllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlligla
vgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkprsggmlfhif
cflfctgeirqeipnadkslemeilkqkyrlkdltfllekqhelikliiqkmeiiseted
ddshcsfqdrfkkeqmeqrnsrwntvlravkakthhlep

    Sequence, based on observed residues (ATOM records):
    >6v9xC (C:)
ksplhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkga
lflsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakaval
llshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitem
ieylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltal
namvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmas
yliktcmilvflssifgyckeagdisnvlewiiyttgiifvlplfveipahlqwqcgaia
vyfywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpf
sspllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnllig
lavgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6v9xD (D:)
mkrslrkmwrpgekkepqgvvyedvpddtedfkeslkvvfegsayglqnfnkqkklkrcd
dmdtfflhyaaaegqielmekitrdsslevlhemddygntplhcaveknqiesvkfllsr
ganpnlrnfnmmaplhiavqgmnnevmkvllehrtidvnlegengntaviiacttnnsea
lqillkkgakpcksnkwgcfpihqaafsgskecmeiilrfgeehgysrqlhinfmnngka
tplhlavqngdlemikmcldngaqidpvekgrctaihfaatqgateivklmissysgsvd
ivnttdgchetmlhraslfdhheladylisvgadinkidsegrsplilatasaswnivnl
llskgaqvdikdnfgrnflhltvqqpyglknlrpefmqmqqikelvmdedndgctplhya
crqggpgsvnnllgfnvsihskskdkksplhfaasygrintcqrllqdisdtrllnegdl
hgmtplhlaaknghdkvvqlllkkgalflsdhngwtalhhasmggytqtmkvildtnlkc
tdrldedgntalhfaareghakavalllshnadivlnkqqasflhlalhnkrkevvltii
rskrwdeclkifshnspgnkcpitemieylpecmkvlldfcmlhstedkscrdyyieynf
kylqcpleftkktptqdviyepltalnamvqnnriellnhpvckeyllmkwlaygfrahm
mnlgsyclglipmtilvvnikpgmafnstgiinetsdhseildttnsyliktcmilvfls
sifgyckeagqifqqkrnyfmdisnvlewiiyttgiifvlplfveipahlqwqcgaiavy
fywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpfss
pllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnlligla
vgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkprsggmlfhif
cflfctgeirqeipnadkslemeilkqkyrlkdltfllekqhelikliiqkmeiiseted
ddshcsfqdrfkkeqmeqrnsrwntvlravkakthhlep

    Sequence, based on observed residues (ATOM records):
    >6v9xD (D:)
ksplhfaasygrintcqrllqdisdtrllnegdlhgmtplhlaaknghdkvvqlllkkga
lflsdhngwtalhhasmggytqtmkvildtnlkctdrldedgntalhfaareghakaval
llshnadivlnkqqasflhlalhnkrkevvltiirskrwdeclkifshnspgnkcpitem
ieylpecmkvlldfcmlhstedkscrdyyieynfkylqcpleftkktptqdviyepltal
namvqnnriellnhpvckeyllmkwlaygfrahmmnlgsyclglipmtilvvnikpgmas
yliktcmilvflssifgyckeagdisnvlewiiyttgiifvlplfveipahlqwqcgaia
vyfywmnfllylqrfencgifivmlevilktllrstvvfiflllafglsfyillnlqdpf
sspllsiiqtfsmmlgdinyresflepylrnelahpvlsfaqlvsftifvpivlmnllig
lavgdiadvqkhaslkriamqvelhtslekklplwflrkvdqkstivypnkslemeilkq
kyrlkdltfllekqhelikliiqkmeiiset