PDB entry 6v6u

View 6v6u on RCSB PDB site
Description: Crystal structure of RhoA-GDP with novel Switch I conformation
Class: hydrolase
Keywords: GTPase, Switch I, Switch II, HYDROLASE
Deposited on 2019-12-06, released 2020-12-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-16, with a file datestamp of 2021-06-11.
Experiment type: XRAY
Resolution: 1.16 Å
R-factor: N/A
AEROSPACI score: 0.76 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RHOA, ARH12, ARHA, RHO12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (Start-182)
      • engineered mutation (26)
    Domains in SCOPe 2.08: d6v6ua_
  • Heterogens: GDP, MG, DIO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6v6uA (A:)
gsmaairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalw
dtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnk
kdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraa
lqa

    Sequence, based on observed residues (ATOM records): (download) 
    >6v6uA (A:)
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalqa