PDB entry 6v63

View 6v63 on RCSB PDB site
Description: setd3 wt in complex with an actin peptide with his73 replaced with glutamine
Deposited on 2019-12-04, released 2020-01-22
The last revision was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin-histidine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Actin-histidine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'Y':
    Compound: Actin, cytoplasmic 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot C9JUM1 (0-End)
      • engineered mutation (7)
  • Chain 'Z':
    Compound: Actin, cytoplasmic 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot C9JUM1 (0-End)
      • engineered mutation (7)
  • Heterogens: GOL, SAH, EDO, ACT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6v63A (A:)
gsmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlve
kirkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaee
lflwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqt
lpseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkds
ftyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecv
alqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevla
ragiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpv
swdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeileka
vksaavnreyyrqqmeekaplpkyeesnlgllessvgdsrlplvlrnleeeagvqdalni
reaiskakatenglvngensipngtrseneslnqeskravedakgsssdstagvke

    Sequence, based on observed residues (ATOM records):
    >6v63A (A:)
vspkeilnltsellqkcsspapgpgkeweeyvqirtlvekirkkqkglsvtfdgkredyf
pdlmkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvl
gplysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqs
tqaihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqip
tedgsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsna
efvihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisa
qllaflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllk
tykttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekapl
pkye

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6v63B (B:)
gsmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlve
kirkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaee
lflwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqt
lpseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkds
ftyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecv
alqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevla
ragiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpv
swdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeileka
vksaavnreyyrqqmeekaplpkyeesnlgllessvgdsrlplvlrnleeeagvqdalni
reaiskakatenglvngensipngtrseneslnqeskravedakgsssdstagvke

    Sequence, based on observed residues (ATOM records):
    >6v63B (B:)
vspkeilnltsellqkcsspapgpgkeweeyvqirtlvekirkkqkglsvtfdgkredyf
pdlmkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvl
gplysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqs
tqaihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqip
tedgsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsna
efvihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisa
qllaflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllk
tykttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekapl
pky

  • Chain 'Y':
    Sequence, based on SEQRES records:
    >6v63Y (Y:)
tlkypieqgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6v63Y (Y:)
tlkypieqgivtnwddmek

  • Chain 'Z':
    Sequence, based on SEQRES records:
    >6v63Z (Z:)
tlkypieqgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6v63Z (Z:)
tlkypieqgivtnwddmek