PDB entry 6v53

View 6v53 on RCSB PDB site
Description: The crystal structure of the 2009 H1N1 PA endonuclease mutant I38T in complex with SJ000985494
Class: viral protein
Keywords: nuclease influenza inhibitor resistance, hydrolase, viral protein
Deposited on 2019-12-03, released 2020-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-09, with a file datestamp of 2020-12-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein
    Species: Influenza A virus (A/Luxembourg/43/2009(H1N1)) [TaxId:655278]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C6H0Y9 (20-69)
      • expression tag (17-19)
      • engineered mutation (57)
      • linker (70-72)
    • Uniprot C6H0Y9 (73-End)
    Domains in SCOPe 2.08: d6v53a1, d6v53a2
  • Heterogens: QPY, QQ4, MN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6v53A (A:)
mgsshhhhhhssglvprgshmedfvrqcfnpmivelaekamkeygedpkietnkfaatct
hlevcfmysdggskhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfie
igvtrrevhiyylekankiksekthihifsftgeematkadytldeesrariktrlftir
qemasrslwdsfrqser

    Sequence, based on observed residues (ATOM records): (download) 
    >6v53A (A:)
gshmedfvrqcfnpmivelaekamkeygedpkietnkfaatcthlevcfmysdggskhrf
eiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekan
kiksekthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqse