PDB entry 6v4h

View 6v4h on RCSB PDB site
Description: crystal structure analysis of zebra fish mdmx
Deposited on 2019-11-27, released 2020-04-22
The last revision was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 1.53 Å
R-factor: N/A
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein Mdm4
    Species: Danio rerio [TaxId:7955]
    Gene: mdm4, mdmx
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZUW7 (Start-102)
      • engineered mutation (42)
      • engineered mutation (91)
  • Chain 'B':
    Compound: Stapled Peptide LSQETF(0EH)DLWKLL(MK8)EN(NH2)
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6V4H
  • Chain 'C':
    Compound: Protein Mdm4
    Species: Danio rerio [TaxId:7955]
    Gene: mdm4, mdmx
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ZUW7 (Start-102)
      • engineered mutation (42)
      • engineered mutation (91)
  • Chain 'D':
    Compound: Stapled Peptide LSQETF(0EH)DLWKLL(MK8)EN(NH2)
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6V4H
  • Heterogens: 0EH, MK8, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6v4hA (A:)
hhhhhhddddkrtlpgegtqvhprapllqilkvagaqeevftvkevmhylgqyimmkqly
dkqrqhivhchddplgellevgsfsvknpsplyemlkrnlvil

    Sequence, based on observed residues (ATOM records):
    >6v4hA (A:)
lpgegtqvhprapllqilkvagaqeevftvkevmhylgqyimmkqlydkqrqhivhchdd
plgellevgsfsvknpsplyemlkrnlvil

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6v4hB (B:)
lsqetfxdlwkllxen

    Sequence, based on observed residues (ATOM records):
    >6v4hB (B:)
qetfxdlwkllxen

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6v4hC (C:)
hhhhhhddddkrtlpgegtqvhprapllqilkvagaqeevftvkevmhylgqyimmkqly
dkqrqhivhchddplgellevgsfsvknpsplyemlkrnlvil

    Sequence, based on observed residues (ATOM records):
    >6v4hC (C:)
lpgegtqvhprapllqilkvagaqeevftvkevmhylgqyimmkqlydkqrqhivhchdd
plgellevgsfsvknpsplyemlkrnlvil

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6v4hD (D:)
lsqetfxdlwkllxen

    Sequence, based on observed residues (ATOM records):
    >6v4hD (D:)
etfxdlwkllxen