PDB entry 6uyn

View 6uyn on RCSB PDB site
Description: Crystal structure of influenza A virus hemagglutinin from A/Ohio/09/2015 bound to the stalk-binding CR6261 antibody Fab
Class: viral protein/immune system
Keywords: hemagglutinin, vaccine design, antibody, Fab, flu, influenza, H1N1, structural genomics, NIAID, Seattle Structural Genomics Center for Infectious Disease, SSGCID, VIRAL PROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2019-11-13, released 2020-09-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin HA1 chain
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6uyna_
  • Chain 'B':
    Compound: Hemagglutinin HA1 chain
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6uynb_
  • Chain 'H':
    Compound: CR6261 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYN (0-End)
  • Chain 'L':
    Compound: CR6261 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYN
    Domains in SCOPe 2.08: d6uynl1
  • Heterogens: NAG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6uynA (A:)
mkanllvllcalaaadadkicigyhannstdtvdtvleknvtvthsvnllenkhngklck
lrgvaplhlgkcniagwllgnpeceslatasswsyivetsssnngtcypgdfinyeelre
qlssvssfekfeifpktsswpnhetnkgvtaacphagtnsfyknliwlvkkensypkini
sytnnrgkevlvlwaihhpptstdqqslyqnansyvfvgssrysrkfepeiatrpkvrgq
agrmnyywtlvepgdkitfeatgnlvvpryafalkrnsgsgiiisetpvhdcdttcqtpn
gaintslpfqnihpvtigecpkyvkstklrmatglrnipsiqsrglfgaiagfieggwtg
midgwygyhhqneqgsgyaadlkstqnaidgitnkvnsviekmntqftavgkefshlerr
ienlnkkvddgfidiwtynaellvllenertldyhdsnvktlyekvrsqlknnakeigng
cfefyhkcddtcmesvkngtydypkyseeaklnreeidgiklestriyqilaiystvass
lvllvslgaisfwmcsngslqcrici

    Sequence, based on observed residues (ATOM records): (download) 
    >6uynA (A:)
dadkicigyhannstdtvdtvleknvtvthsvnllenkhngklcklrgvaplhlgkcnia
gwllgnpeceslatasswsyivetsssnngtcypgdfinyeelreqlssvssfekfeifp
ktsswpnhetnkgvtaacphagtnsfyknliwlvkkensypkinisytnnrgkevlvlwa
ihhpptstdqqslyqnansyvfvgssrysrkfepeiatrpkvrgqagrmnyywtlvepgd
kitfeatgnlvvpryafalkrnsgsgiiisetpvhdcdttcqtpngaintslpfqnihpv
tigecpkyvkstklrmatglrnipsi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6uynB (B:)
mkanllvllcalaaadadkicigyhannstdtvdtvleknvtvthsvnllenkhngklck
lrgvaplhlgkcniagwllgnpeceslatasswsyivetsssnngtcypgdfinyeelre
qlssvssfekfeifpktsswpnhetnkgvtaacphagtnsfyknliwlvkkensypkini
sytnnrgkevlvlwaihhpptstdqqslyqnansyvfvgssrysrkfepeiatrpkvrgq
agrmnyywtlvepgdkitfeatgnlvvpryafalkrnsgsgiiisetpvhdcdttcqtpn
gaintslpfqnihpvtigecpkyvkstklrmatglrnipsiqsrglfgaiagfieggwtg
midgwygyhhqneqgsgyaadlkstqnaidgitnkvnsviekmntqftavgkefshlerr
ienlnkkvddgfidiwtynaellvllenertldyhdsnvktlyekvrsqlknnakeigng
cfefyhkcddtcmesvkngtydypkyseeaklnreeidgiklestriyqilaiystvass
lvllvslgaisfwmcsngslqcrici

    Sequence, based on observed residues (ATOM records): (download) 
    >6uynB (B:)
glfgaiagfieggwtgmidgwygyhhqneqgsgyaadlkstqnaidgitnkvnsviekmn
tqftavgkefshlerrienlnkkvddgfidiwtynaellvllenertldyhdsnvktlye
kvrsqlknnakeigngcfefyhkcddtcmesvkngtydypkyseeak

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6uynL (L:)
qsvltqppsvsaapgqkvtiscsgsssnigndyvswyqqlpgtapklliydnnkrpsgip
drfsgsksgtsatlgitglqtgdeanyycatwdrrptayvvfgggtkltvlgaaagqpka
apsvtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnk
yaassylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6uynL (L:)
vltqppsvsaapgqkvtiscsgsssnigndyvswyqqlpgtapklliydnnkrpsgipdr
fsgsksgtsatlgitglqtgdeanyycatwdrrptayvvfgggtkltvleelqankatlv
clisdfygvetttpskqsnnkyaassyls