PDB entry 6uym

View 6uym on RCSB PDB site
Description: structure of hepatitis c virus envelope glycoprotein e2mc3-v6 redesigned core from genotype 1a bound to broadly neutralizing antibody ar3c
Deposited on 2019-11-13, released 2020-04-22
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab AR3C heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYM
  • Chain 'B':
    Compound: Fab AR3C light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYM
  • Chain 'E':
    Compound: Envelope glycoprotein E2
    Species: Hepatitis C virus (isolate H) [TaxId:11108]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYM (Start-175)
  • Chain 'F':
    Compound: Envelope glycoprotein E2
    Species: Hepatitis C virus (isolate H) [TaxId:11108]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYM (Start-175)
  • Chain 'H':
    Compound: Fab AR3C heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYM
  • Chain 'L':
    Compound: Fab AR3C light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UYM
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6uymA (A:)
evqlleqsgaevkkpgssvkvscetsggtfdnyalnwvrqapgqglewiggvvplfgttr
naqkfqgrvtisddkstgtghmelrslrsedtavyycvrsvtprycgggfcygefdywgq
gtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscgs

    Sequence, based on observed residues (ATOM records):
    >6uymA (A:)
qlleqsgaevkkpgssvkvscetsggtfdnyalnwvrqapgqglewiggvvplfgttrna
qkfqgrvtisddkstgtghmelrslrsedtavyycvrsvtprycgggfcygefdywgqgt
lvtvssastkgpsvfplapssgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6uymB (B:)
eieltqspatlsvspgeratlscrasqsvssnlawyqqkpgqaprlliygastratgipa
rfsgsgsgteftltvsrlepedsavyfcqqyyrspltfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6uymB (B:)
eltqspatlsvspgeratlscrasqsvssnlawyqqkpgqaprlliygastratgiparf
sgsgsgteftltvsrlepedsavyfcqqyyrspltfgggtkveikrtvaapsvfifppsd
eqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltls
kadyekhkvyacevthqglsspvtksfn

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6uymE (E:)
qlintngswhinstalncneslntgwlaglfyqhkfdssgcpktevhyprpcgivpaksv
cgpvycftpspvvvgttdrsgaptyswgandtdvfvlnntgnwfgctwmnstgftkvcga
ppggptdggsgpwitprcmvdypyrlwhypctinytifkvrmyvggvehrleaacn

    Sequence, based on observed residues (ATOM records):
    >6uymE (E:)
hinstalncneslntgwlaglfyqhkfdssgcyprpcgivpaksvcgpvycftpspvvvg
ttdrsgaptyswgandtdvfvlnnwfgctwmnstgftkvcggpwitprcmvdypyrlwhy
pctinytifkvrmyvvehrleaacn

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6uymF (F:)
qlintngswhinstalncneslntgwlaglfyqhkfdssgcpktevhyprpcgivpaksv
cgpvycftpspvvvgttdrsgaptyswgandtdvfvlnntgnwfgctwmnstgftkvcga
ppggptdggsgpwitprcmvdypyrlwhypctinytifkvrmyvggvehrleaacn

    Sequence, based on observed residues (ATOM records):
    >6uymF (F:)
hinstalncneslntgwlaglfyqprpcgivpaksvcgpvycftpspvvvgttdrsgapt
yswgandtdvfvlnnwfgctwmnstgftkvcgpwitprcmvdypyrlwhypctinytifk
vrmyvggvehrleaacn

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6uymH (H:)
evqlleqsgaevkkpgssvkvscetsggtfdnyalnwvrqapgqglewiggvvplfgttr
naqkfqgrvtisddkstgtghmelrslrsedtavyycvrsvtprycgggfcygefdywgq
gtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscgs

    Sequence, based on observed residues (ATOM records):
    >6uymH (H:)
lleqsgaevkkpgssvkvscetsggtfdnyalnwvrqapgqglewiggvvplfgttrnaq
kfqgrvtisddkstgtghmelrslrsedtavyycvrsvtprycgggfcygefdywgqgtl
vtvssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6uymL (L:)
eieltqspatlsvspgeratlscrasqsvssnlawyqqkpgqaprlliygastratgipa
rfsgsgsgteftltvsrlepedsavyfcqqyyrspltfgggtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6uymL (L:)
eltqspatlsvspgeratlscrasqsvssnlawyqqkpgqaprlliygastratgiparf
sgsgsgteftltvsrlepedsavyfcqqyyrspltfgggtkveikrtvaapsvfifppsd
eqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltls
kadyekhkvyacevthqglsspvtksfnrge