PDB entry 6uxo

View 6uxo on RCSB PDB site
Description: crystal structure of bak core domain bh3-groove-dimer in complex with ddm
Deposited on 2019-11-07, released 2020-09-02
The last revision was dated 2020-11-18, with a file datestamp of 2020-11-13.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16611 (4-End)
      • expression tag (3)
  • Chain 'D':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16611 (4-End)
      • expression tag (3)
  • Chain 'H':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16611 (4-End)
      • expression tag (3)
  • Chain 'J':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: bcl-2 homologous antagonist/killer
    Species: Homo sapiens [TaxId:9606]
    Gene: BAK1, BAK, BCL2L7, CDN1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: LMT, SO4, ACT, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6uxoA (A:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoA (A:)
sstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgr
vvallgfgyrlalhvyqhgl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6uxoB (B:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoB (B:)
stmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgrv
vallgfgyrlalhvyqhg

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6uxoC (C:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoC (C:)
gsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwg
rvvallgfgyrlalhvyqhgl

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6uxoD (D:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoD (D:)
stmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgrv
vallgfgyrlalhvyqhgl

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6uxoE (E:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoE (E:)
sstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgr
vvallgfgyrlalhvyqhgl

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6uxoF (F:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoF (F:)
stmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgrv
vallgfgyrlalhvyqhgl

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6uxoG (G:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoG (G:)
gsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwg
rvvallgfgyrlalhvyqhgl

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6uxoH (H:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoH (H:)
stmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgrv
vallgfgyrlalhvyqhg

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6uxoI (I:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoI (I:)
gsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwg
rvvallgfgyrlalhvyqhgl

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6uxoJ (J:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoJ (J:)
stmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgrv
vallgfgyrlalhvyqhg

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6uxoK (K:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoK (K:)
stmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgrv
vallgfgyrlalhvyqhgl

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6uxoL (L:)
gplgsstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesgi
nwgrvvallgfgyrlalhvyqhglt

    Sequence, based on observed residues (ATOM records):
    >6uxoL (L:)
sstmgqvgrqlaiigddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgr
vvallgfgyrlalhvyqhglt