PDB entry 6us2

View 6us2 on RCSB PDB site
Description: MTH1 in complex with compound 5
Class: hydrolase/hydrolase inhibitor
Keywords: Hydrolase, NUDT1, Nudix hydrolase, inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2019-10-24, released 2020-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-01, with a file datestamp of 2020-03-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 7,8-dihydro-8-oxoguanine triphosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: NUDT1, MTH1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6us2a_
  • Heterogens: S3O, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6us2A (A:)
gshmgasrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqees
gltvdalhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmw
pddsywfplllqkkkfhgyfkfqgqdtildytlrevdtv

    Sequence, based on observed residues (ATOM records): (download) 
    >6us2A (A:)
asrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesgltvd
alhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpddsy
wfplllqkkkfhgyfkfqgqdtildytlrevdtv