PDB entry 6up5

View 6up5 on RCSB PDB site
Description: Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure
Class: isomerase
Keywords: glycolytic enzyme, alpha beta barrel, ISOMERASE
Deposited on 2019-10-16, released 2020-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-15, with a file datestamp of 2020-07-10.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: triosephosphate isomerase
    Species: Homo sapiens [TaxId:9606]
    Gene: TPI1, TPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6up5a_
  • Chain 'B':
    Compound: triosephosphate isomerase
    Species: Homo sapiens [TaxId:9606]
    Gene: TPI1, TPI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6up5b_
  • Heterogens: PGA, GOL, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6up5A (A:)
gshmapsrkffvggnwkmngrkqslgeligtlnaakvpadtevvcapptayidfarqkld
pkiavaaqncykvtngaftgeispgmikdcgatwvvlghserrhvfgesdeligqkvaha
laeglgviacigekldereagitekvvfeqtkviadnvkdwskvvlayepvwaigtgkta
tpqqaqevheklrgwlksnvsdavaqstriiyggsvtgatckelasqpdvdgflvggasl
kpefvdiinakq

    Sequence, based on observed residues (ATOM records): (download) 
    >6up5A (A:)
srkffvggnwkmngrkqslgeligtlnaakvpadtevvcapptayidfarqkldpkiava
aqncykvtngaftgeispgmikdcgatwvvlghserrhvfgesdeligqkvahalaeglg
viacigekldereagitekvvfeqtkviadnvkdwskvvlayepvwaigtgktatpqqaq
evheklrgwlksnvsdavaqstriiyggsvtgatckelasqpdvdgflvggaslkpefvd
iinakq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6up5B (B:)
gshmapsrkffvggnwkmngrkqslgeligtlnaakvpadtevvcapptayidfarqkld
pkiavaaqncykvtngaftgeispgmikdcgatwvvlghserrhvfgesdeligqkvaha
laeglgviacigekldereagitekvvfeqtkviadnvkdwskvvlayepvwaigtgkta
tpqqaqevheklrgwlksnvsdavaqstriiyggsvtgatckelasqpdvdgflvggasl
kpefvdiinakq

    Sequence, based on observed residues (ATOM records): (download) 
    >6up5B (B:)
psrkffvggnwkmngrkqslgeligtlnaakvpadtevvcapptayidfarqkldpkiav
aaqncykvtngaftgeispgmikdcgatwvvlghserrhvfgesdeligqkvahalaegl
gviacigekldereagitekvvfeqtkviadnvkdwskvvlayepvwaigtgktatpqqa
qevheklrgwlksnvsdavaqstriiyggsvtgatckelasqpdvdgflvggaslkpefv
diinakq