PDB entry 6uo3

View 6uo3 on RCSB PDB site
Description: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) complexed with AR-42
Class: Hydrolase/Hydrolase Inhibitor
Keywords: Histone Deacetylase, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2019-10-14, released 2019-12-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 1.09 Å
R-factor: N/A
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hdac6
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed):
    • Uniprot F8W4B7 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.08: d6uo3a1, d6uo3a2
  • Heterogens: QCP, ZN, K, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6uo3A (A:)
snaggsatgtglvyvdaftrfhclwdashpecparvstvmemletegllgrcvqvearav
tedelllvhtkeyvelmkstqnmteeelktlaekydsvylhpgffssaclsvgsvlqlvd
kvmtsqlrngfsinrppghhaqadkmngfcmfnnlaiaaryaqkrhrvqrvlivdwdvhh
gqgiqyifeedpsvlyfsvhryedgsfwphlkesdsssvgsgagqgyninlpwnkvgmes
gdyitafqqlllpvayefqpqlvlvaagfdavigdpkggmqvspecfsilthmlkgvaqg
rlvlaleggynlqstaegvcasmrsllgdpcphlpssgapcesalksisktisdlypfwk
slqtfe

    Sequence, based on observed residues (ATOM records): (download) 
    >6uo3A (A:)
gsatgtglvyvdaftrfhclwdashpecparvstvmemletegllgrcvqvearavtede
lllvhtkeyvelmkstqnmteeelktlaekydsvylhpgffssaclsvgsvlqlvdkvmt
sqlrngfsinrppghhaqadkmngfcmfnnlaiaaryaqkrhrvqrvlivdwdvhhgqgi
qyifeedpsvlyfsvhryedgsfwphlkesdsssvgsgagqgyninlpwnkvgmesgdyi
tafqqlllpvayefqpqlvlvaagfdavigdpkggmqvspecfsilthmlkgvaqgrlvl
aleggynlqstaegvcasmrsllgdpcphlpssgapcesalksisktisdlypfwkslq