PDB entry 6umu

View 6umu on RCSB PDB site
Description: Human apo PD-1 triple mutant
Class: immune system
Keywords: PD-1, immune checkpoint, IMMUNE SYSTEM
Deposited on 2019-10-10, released 2019-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 1.18 Å
R-factor: N/A
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Programmed cell death protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Pdcd1, Pd1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15116 (1-End)
      • initiating methionine (0)
      • engineered mutation (44)
      • conflict (61)
      • engineered mutation (100)
    Domains in SCOPe 2.08: d6umua_
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6umuA (A:)
mnpptfspallvvtegdnatftcsfsntsesfvlnwyrmspsgqpdklaafpedrsqpgq
dsrfrvtqlpngrdfhmsvvrarrndsgtylcgaislapkvqikeslraelrvterraeg
swshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6umuA (A:)
mnpptfspallvvtegdnatftcsfsntsesfvlnwyrmqpdklaafpedrsqpgqdsrf
rvtqlpngrdfhmsvvrarrndsgtylcgaislapkvqikeslraelrvter