PDB entry 6umt

View 6umt on RCSB PDB site
Description: High-affinity human PD-1 PD-L2 complex
Class: immune system
Keywords: PD-1, PD-L2, immune checkpoint, IMMUNE SYSTEM
Deposited on 2019-10-10, released 2019-11-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Programmed cell death protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Pdcd1, Pd1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15116 (19-End)
      • conflict (35)
      • conflict (44)
      • engineered mutation (60)
      • engineered mutation (62)
      • conflict (79)
      • conflict (102)
      • engineered mutation (118)
    Domains in SCOPe 2.07: d6umta_
  • Chain 'B':
    Compound: Programmed cell death 1 ligand 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BQ51
      • conflict (36)
      • conflict (63)
    Domains in SCOPe 2.07: d6umtb_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6umtA (A:)
mgwsciilflvatatgvhsnpptfspallvvtegdsatftcsfsstsesfvlnwyrmsps
gqpdklaafpedrsqpgqdsrfrvtqlpngrdfhmsvvrarrddsgtylcgaislapkvq
ikeslraelrvterraepea

    Sequence, based on observed residues (ATOM records): (download) 
    >6umtA (A:)
npptfspallvvtegdsatftcsfsstsesfvlnwyrmspsgqpdklaafpesrfrvtql
pngrdfhmsvvrarrddsgtylcgaislapkvqikeslraelrvterra

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6umtB (B:)
miflllmlslelqlhqiaalftvtvpkelyiiehgsdvtlecnfdtgshvnlgaitaslq
kveddtsphreratlleeqlplgkasfhipqvqvrdegqyqciiiygvawdykyltlkvk
asy

    Sequence, based on observed residues (ATOM records): (download) 
    >6umtB (B:)
lftvtvpkelyiiehgsdvtlecnfdtgshvnlgaitaslqkvedphreratlleeqlpl
gkasfhipqvqvrdegqyqciiiygvawdykyltlkvka