PDB entry 6umm

View 6umm on RCSB PDB site
Description: a complete structure of the esx-3 translocon complex
Deposited on 2019-10-09, released 2019-10-23
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3.7 Å
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ESX-3 secretion system protein EccE3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ESX-3 secretion system protein EccD3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: ESX-3 secretion system protein EccD3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ESX-3 secretion system ATPase EccB3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: ESX-3 secretion system protein EccC3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: ESX-3 secretion system protein EccE3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: ESX-3 secretion system protein EccD3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: ESX-3 secretion system protein EccD3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: ESX-3 secretion system ATPase EccB3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: ESX-3 secretion system protein EccC3
    Species: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6ummA (A:)
mtarialaslfvvaavlaqpwqtttqrwvlgvsiaavivllawwkgmflttrigralamv
rrnraedtvetdahratvvlrvdpaapaqlpvvvgyldrygitcdkvrithrdaggtrrs
wisltvdavdnlaalqarsariplqdttevvgrrladhlreqgwtvtvvegvdtplpvsg
ketwrgvaddagvvaayrvkvddrldevlaeighlpaeetwtaleftgspaeplltvcaa
vrtsdrpaakaplagltpargrhrpalaalnplsterldgtavpl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ummB (B:)
msentvmpivrvavlaagddggrltemalpselplreilpavqrivqparendgaadpaa
apnpvrlslapiggapfsldatldtvgvvdgdllalqavpsgppaprivediadaavifs
earrrqwgpthiargaalaliglilvgtglsvahrvitgdllgqfivsgialatviaala
vrnrsavlatslavtalvpvaaafalgvpgdfgapnvllaaagvaawslismagspddrg
iavftatavtgvgvllvagaaslwvissdvigcalvllglivtvqaaqlsamwarfplpv
ipapgdptpaarplsvladlprrvrvsqahqtgviaagvllgvagsvalvssanaspwaw
yivvaaaagaalrarvwdsaackawllghsyllavallvafvigdryqaalwalaalavl
vlvwivaalnpkiaspdtyslpmrrmvgflatgldaslipvmallvglfslvldr

    Sequence, based on observed residues (ATOM records):
    >6ummB (B:)
mpivrvavlaagddggrltemalpselplreilpavqrivqpaapnpvrlslapiggapf
sldatldtvgvvdgdllalqavpsgppaprivediadaavifsearrrqwgpthiargaa
laliglilvgtglsvahrvitgdllgqfivsgialatviaalavrnrsavlatslavtal
vpvaaafalgvpgdfgapnvllaaagvaawslismagspddrgiavftatavtgvgvllv
agaaslwvissdvigcalvllglivtvqaaqlsamwarplsvladlprrvrvsqahqtgv
iaagvllgvagsvalvssanaspwawyivvaaaagaalrarvwdsaackawllghsylla
vallvafvigdryqaalwalaalavlvlvwivaalnpkiaspdtyslpmrrmvgflatgl
daslipvmallvglfslvldr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ummC (C:)
msentvmpivrvavlaagddggrltemalpselplreilpavqrivqparendgaadpaa
apnpvrlslapiggapfsldatldtvgvvdgdllalqavpsgppaprivediadaavifs
earrrqwgpthiargaalaliglilvgtglsvahrvitgdllgqfivsgialatviaala
vrnrsavlatslavtalvpvaaafalgvpgdfgapnvllaaagvaawslismagspddrg
iavftatavtgvgvllvagaaslwvissdvigcalvllglivtvqaaqlsamwarfplpv
ipapgdptpaarplsvladlprrvrvsqahqtgviaagvllgvagsvalvssanaspwaw
yivvaaaagaalrarvwdsaackawllghsyllavallvafvigdryqaalwalaalavl
vlvwivaalnpkiaspdtyslpmrrmvgflatgldaslipvmallvglfslvldr

    Sequence, based on observed residues (ATOM records):
    >6ummC (C:)
mpivrvavlaagddggrltemalpselplreilpavqrivqpalslapiggapfsldatl
dtvgvvdgdllalqavpsgppaprivediadaavifsearrrqwgpthiargaalaligl
ilvgtglsvahrvitgdllgqfivsgialatviaalavrnrsavlatslavtalvpvaaa
falgvpgdfgapnvllaaagvaawslismagspddrgiavftatavtgvgvllvagaasl
wvissdvigcalvllglivtvqaaqlsamwarfplpvipapgdptpaarplsvladlprr
vrvsqahqtgviaagvllgvagsvalvssanaspwawyivvaaaagaalrarvwdsaack
awllghsyllavallvafvigdryqaalwalaalavlvlvwivaalnpkiaspdtyslpm
rrmvgflatgldaslipvmallvglfslvldr

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6ummD (D:)
fssrtpvnenpdgvqyrrgfvtrhqvsgwrfvmrriasgvalhdtrmlvdplrtqsravl
tgalilvtglvgcfifslfrp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6ummE (E:)
msrlifehqrrltppttrkgtitiepppqlprvvppsllrrvlpflivilivgmivalfa
tgmrlisptmlffpfvlllaatalyrggdnkmrteevdaeradylrylsvvrdnvrahaa
eqraalewshpepevlatipgtrrqwerdprdrdflvlragrhdvpldaalkvkdtadei
dlepvahsalrglldvqrtvrdaptgldvaklaritvigeadearaairawiaqavtwhd
ptmlgvalaapdlesgdwswlkwlphvdvpneadgvgparylttstaelrerlapaladr
plfpaesgaalkhllvvlddpdadpddiarkpgltgvtvihrttelpnreqypdperpil
rvadgrierwqvggwqpcvdvadamsaaeaahiarrlsrwdsn

    Sequence, based on observed residues (ATOM records):
    >6ummE (E:)
msrlifehqrrltppttrkgtitiepppqlprvteevdaeradylrylsvvrdnvrahaa
eqraalewshpepevlatipgtrrqwerdprdrdflvlragrhdvpldaalkvkdtadei
dlepvahsalrglldvqrtvrdaptgldvaklaritvigeadearaairawiaqavtwhd
ptmlgvalaapdlesgdwswlkwlphvdvpneadgvgparylttstaelrerlapaladr
plfpaesgaalkhllvvlddpdadpddiarkpgltgvtvihrttelpnreqypdperpil
rvadgrierwqvggwqpcvdvadamsaaeaahiarrlsrwdsn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >6ummF (F:)
mtarialaslfvvaavlaqpwqtttqrwvlgvsiaavivllawwkgmflttrigralamv
rrnraedtvetdahratvvlrvdpaapaqlpvvvgyldrygitcdkvrithrdaggtrrs
wisltvdavdnlaalqarsariplqdttevvgrrladhlreqgwtvtvvegvdtplpvsg
ketwrgvaddagvvaayrvkvddrldevlaeighlpaeetwtaleftgspaeplltvcaa
vrtsdrpaakaplagltpargrhrpalaalnplsterldgtavpl

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6ummG (G:)
msentvmpivrvavlaagddggrltemalpselplreilpavqrivqparendgaadpaa
apnpvrlslapiggapfsldatldtvgvvdgdllalqavpsgppaprivediadaavifs
earrrqwgpthiargaalaliglilvgtglsvahrvitgdllgqfivsgialatviaala
vrnrsavlatslavtalvpvaaafalgvpgdfgapnvllaaagvaawslismagspddrg
iavftatavtgvgvllvagaaslwvissdvigcalvllglivtvqaaqlsamwarfplpv
ipapgdptpaarplsvladlprrvrvsqahqtgviaagvllgvagsvalvssanaspwaw
yivvaaaagaalrarvwdsaackawllghsyllavallvafvigdryqaalwalaalavl
vlvwivaalnpkiaspdtyslpmrrmvgflatgldaslipvmallvglfslvldr

    Sequence, based on observed residues (ATOM records):
    >6ummG (G:)
mpivrvavlaagddggrltemalpselplreilpavqrivqpaapnpvrlslapiggapf
sldatldtvgvvdgdllalqavpsgppaprivediadaavifsearrrqwgpthiargaa
laliglilvgtglsvahrvitgdllgqfivsgialatviaalavrnrsavlatslavtal
vpvaaafalgvpgdfgapnvllaaagvaawslismagspddrgiavftatavtgvgvllv
agaaslwvissdvigcalvllglivtvqaaqlsamwarplsvladlprrvrvsqahqtgv
iaagvllgvagsvalvssanaspwawyivvaaaagaalrarvwdsaackawllghsylla
vallvafvigdryqaalwalaalavlvlvwivaalnpkiaspdtyslpmrrmvgflatgl
daslipvmallvglfslvldr

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ummH (H:)
msentvmpivrvavlaagddggrltemalpselplreilpavqrivqparendgaadpaa
apnpvrlslapiggapfsldatldtvgvvdgdllalqavpsgppaprivediadaavifs
earrrqwgpthiargaalaliglilvgtglsvahrvitgdllgqfivsgialatviaala
vrnrsavlatslavtalvpvaaafalgvpgdfgapnvllaaagvaawslismagspddrg
iavftatavtgvgvllvagaaslwvissdvigcalvllglivtvqaaqlsamwarfplpv
ipapgdptpaarplsvladlprrvrvsqahqtgviaagvllgvagsvalvssanaspwaw
yivvaaaagaalrarvwdsaackawllghsyllavallvafvigdryqaalwalaalavl
vlvwivaalnpkiaspdtyslpmrrmvgflatgldaslipvmallvglfslvldr

    Sequence, based on observed residues (ATOM records):
    >6ummH (H:)
mpivrvavlaagddggrltemalpselplreilpavqrivqpalslapiggapfsldatl
dtvgvvdgdllalqavpsgppaprivediadaavifsearrrqwgpthiargaalaligl
ilvgtglsvahrvitgdllgqfivsgialatviaalavrnrsavlatslavtalvpvaaa
falgvpgdfgapnvllaaagvaawslismagspddrgiavftatavtgvgvllvagaasl
wvissdvigcalvllglivtvqaaqlsamwarfplpvipapgdptpaarplsvladlprr
vrvsqahqtgviaagvllgvagsvalvssanaspwawyivvaaaagaalrarvwdsaack
awllghsyllavallvafvigdryqaalwalaalavlvlvwivaalnpkiaspdtyslpm
rrmvgflatgldaslipvmallvglfslvldr

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6ummI (I:)
fssrtpvnenpdgvqyrrgfvtrhqvsgwrfvmrriasgvalhdtrmlvdplrtqsravl
tgalilvtglvgcfifslfrp

    Sequence, based on observed residues (ATOM records):
    >6ummI (I:)
vtrhqvsgwrfvmrriasgvalhdtrmlvdplrtqsravltgalilvtglvgcfifslfr
p

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6ummJ (J:)
msrlifehqrrltppttrkgtitiepppqlprvvppsllrrvlpflivilivgmivalfa
tgmrlisptmlffpfvlllaatalyrggdnkmrteevdaeradylrylsvvrdnvrahaa
eqraalewshpepevlatipgtrrqwerdprdrdflvlragrhdvpldaalkvkdtadei
dlepvahsalrglldvqrtvrdaptgldvaklaritvigeadearaairawiaqavtwhd
ptmlgvalaapdlesgdwswlkwlphvdvpneadgvgparylttstaelrerlapaladr
plfpaesgaalkhllvvlddpdadpddiarkpgltgvtvihrttelpnreqypdperpil
rvadgrierwqvggwqpcvdvadamsaaeaahiarrlsrwdsn

    Sequence, based on observed residues (ATOM records):
    >6ummJ (J:)
msrlifehqrrltppttrkgtitiepppqlprvteevdaeradylrylsvvrdnvrahaa
eqraalewshpepevlatipgtrrqwerdprdrdflvlragrhdvpldaalkvkdtadei
dlepvahsalrglldvqrtvrdaptgldvaklaritvigeadearaairawiaqavtwhd
ptmlgvalaapdlesgdwswlkwlphvdvpneadgvgparylttstaelrerlapaladr
plfpaesgaalkhllvvlddpdadpddiarkpgltgvtvihrttelpnreqypdperpil
rvadgrierwqvggwqpcvdvadamsaaeaahiarrlsrwdsn