PDB entry 6um8

View 6um8 on RCSB PDB site
Description: HIV Integrase in complex with Compound-14
Class: TRANSFERASE,Hydrolase
Keywords: DNA Integration, AIDS, RNASEH, LEDGF, ENDONUCLEASE, HIV-1 integrase, TRANSFERASE, Hydrolase
Deposited on 2019-10-09, released 2020-03-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q76353 (10-End)
      • conflict (84)
      • conflict (138)
    Domains in SCOPe 2.07: d6um8a_
  • Chain 'B':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q76353 (10-End)
      • expression tag (9)
      • conflict (84)
      • conflict (138)
    Domains in SCOPe 2.07: d6um8b1, d6um8b2
  • Heterogens: QCG, 1PE, PEG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6um8A (A:)
gshmhgqvdsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklag
rwpvktvhtdngsnftsttvkaacewagikqefgipynpqsqgviesmnkelkkiigqvr
dqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6um8A (A:)
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacewagikqefgviesmnkelkkiigqvrdqaehlktavqmavfihnk
krgysagerivdiiatdiq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6um8B (B:)
gshmhgqvdsspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklag
rwpvktvhtdngsnftsttvkaacewagikqefgipynpqsqgviesmnkelkkiigqvr
dqaehlktavqmavfihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >6um8B (B:)
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacewagikqefgviesmnkelkkiigqvrdqaehlktavqmavfihn
kkrkgysagerivdiiatdiq