PDB entry 6um4

View 6um4 on RCSB PDB site
Description: crystal structure of malate dehydrogenase from naegleria fowleri atcc 30863
Deposited on 2019-10-09, released 2019-10-23
The last revision was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'B':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'C':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'D':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'E':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'F':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'G':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'H':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'I':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'J':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'K':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Chain 'L':
    Compound: malate dehydrogenase
    Species: Naegleria fowleri [TaxId:5763]
    Gene: mRNA1_NF0021050
    Database cross-references and differences (RAF-indexed):
    • PDB 6UM4
  • Heterogens: EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6um4A (A:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4A (A:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6um4B (B:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4B (B:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6um4C (C:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4C (C:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6um4D (D:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4D (D:)
lappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmelddg
afplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkqa
ngdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdisr
faiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssaa
saadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpin
sfsadrinasvkelieekkivenll

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6um4E (E:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4E (E:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6um4F (F:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4F (F:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6um4G (G:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4G (G:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6um4H (H:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4H (H:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6um4I (I:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4I (I:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6um4J (J:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4J (J:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprmeradvmkdnaaifkaqgealnkqang
dvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdisrfa
iwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssaasa
adaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpinsf
sadrinasvkelieekkivenll

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6um4K (K:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4K (K:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6um4L (L:)
mahhhhhhmkrlvpqfskssrngvrhystlkqrgekmdaelsatrtplermllgkqtknd
fanlnikdpktvaqwlnksaregpkyltkdvdqlappvtitvsgacgqiansllfriang
emlgenqpvklrllerpeamkalegvkmelddgafplleeiyltdsendafrgadyaill
ggkprgpgmeradvmkdnaaifkaqgealnkqangdvlvlivanpantnamitsanapdi
ppenitamtrldhdrglaqvaakvgcnitdisrfaiwgnhsatqypdlsfttikgqwgln
vindeqwitnefipnvqqrgaaiikargkssaasaadaaikhmhdwvlgnsewvsmaips
rgqygiprgiwcsmpvqcfgagkygvieglpinsfsadrinasvkelieekkivenllpn
pvyrlvevdkvniisksyisenkq

    Sequence, based on observed residues (ATOM records):
    >6um4L (L:)
qlappvtitvsgacgqiansllfriangemlgenqpvklrllerpeamkalegvkmeldd
gafplleeiyltdsendafrgadyaillggkprgpgmeradvmkdnaaifkaqgealnkq
angdvlvlivanpantnamitsanapdippenitamtrldhdrglaqvaakvgcnitdis
rfaiwgnhsatqypdlsfttikgqwglnvindeqwitnefipnvqqrgaaiikargkssa
asaadaaikhmhdwvlgnsewvsmaipsrgqygiprgiwcsmpvqcfgagkygvieglpi
nsfsadrinasvkelieekkivenll