PDB entry 6uli

View 6uli on RCSB PDB site
Description: molecular basis for tumor infiltrating tcr recognition of hotspot kras-g12d mutation
Deposited on 2019-10-08, released 2020-05-27
The last revision was dated 2020-06-17, with a file datestamp of 2020-06-12.
Experiment type: XRAY
Resolution: 1.88 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-Cw, HLA-C
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • initiating methionine (0)
  • Chain 'C':
    Compound: gly-ala-asp-gly-val-gly-lys-ser-ala
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01111 (0-8)
      • engineered mutation (2)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6uliA (A:)
cshsmryfytavsrpgrgeprfiavgyvddtqfvqfdsdaasprgeprapwveqegpeyw
dretqkykrqaqtdrvslrnlrgyynqseagshtlqrmygcdlgpdgrllrgynqfaydg
kdyialnedlrswtaadkaaqitqrkweaareaeqrraylegtcvewlrrylengkktlq
raehpkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpepltlrw

    Sequence, based on observed residues (ATOM records):
    >6uliA (A:)
shsmryfytavsrpgrgeprfiavgyvddtqfvqfdsdaasprgeprapwveqegpeywd
retqkykrqaqtdrvslrnlrgyynqseagshtlqrmygcdlgpdgrllrgynqfaydgk
dyialnedlrswtaadkaaqitqrkweaareaeqrraylegtcvewlrrylengkktlqr
aehpkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgtf
qkwaavvvpsgeeqrytchvqheglpepltlrw

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6uliB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records):
    >6uliB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6uliC (C:)
gadgvgksa