PDB entry 6ulc

View 6ulc on RCSB PDB site
Description: structure of full-length, fully glycosylated, non-modified hiv-1 gp160 bound to pg16 fab at a nominal resolution of 4.6 angstrom
Deposited on 2019-10-07, released 2020-04-29
The last revision was dated 2020-09-09, with a file datestamp of 2020-09-04.
Experiment type: EM
Resolution: 4.6 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: envelope glycoprotein gp120,envelope glycoprotein gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: envelope glycoprotein gp41
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: envelope glycoprotein gp120,envelope glycoprotein gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: envelope glycoprotein gp41
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: envelope glycoprotein gp120,envelope glycoprotein gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: envelope glycoprotein gp41
    Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Antibody PG16 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ULC
  • Chain 'L':
    Compound: Antibody PG16 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ULC
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ulcA (A:)
mrvrgiqrncqhlwrwgtlilgmlmicsaaenlwvtvyygvpvwkdaettlfcasdakay
dtevhnvwathacvptdpnpqeiymenvteefnmwknnmveqmhtdiislwdqslkpcvq
ltplcvtldcsynitnnitnsitnssvnmreeikncsfnmttelrdknrkvyslfykldv
vqinngnnssnlyrlincntsaltqacpkvtfepipirycapagyailkcndkefngtgl
cknvstvqcthgirpvvstqlllngslaegkvmirsenitnnvkniivqlnetvtinctr
pnnntrksvrigpgqtfyatgdiigdirqahcnvsgsqwnralhqvvgqlreywnttiif
knssggdleitthsfncggeffycntsglfnsnwthndtasmkpndtitlpcrikqiinm
wqrvgqaiyappiqgvircesnitgliltrdgggninesqifrpgggdmrdnwrselyky
kvvrieplgvaptkakrrvverekr

    Sequence, based on observed residues (ATOM records):
    >6ulcA (A:)
enlwvtvyygvpvwkdaettlfcasdakaydtevhnvwathacvptdpnpqeiymenvte
efnmwknnmveqmhtdiislwdqslkpcvqltplcvtldcsynitnnitnsitnssvnmr
eeikncsfnmttelrdknrkvyslfykldvvqinngnnssnlyrlincntsaltqacpkv
tfepipirycapagyailkcndkefngtglcknvstvqcthgirpvvstqlllngslaeg
kvmirsenitnnvkniivqlnetvtinctrpnnntrksvrigpgqtfyatgdiigdirqa
hcnvsgsqwnralhqvvgqlreywnttiifknssggdleitthsfncggeffycntsglf
nsnwthndtasmkpndtitlpcrikqiinmwqrvgqaiyappiqgvircesnitgliltr
dgggninesqifrpgggdmrdnwrselykykvvrieplgvaptkakrrvve

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ulcB (B:)
avvelgavfigflgtagstmgaasitltvqvrkllsgivqqqsnllraieaqqhllkltv
wgikqlqarvlaverylrdqqllgiwgcsgklicttnvpwnsswsnksereiwenmtwlq
wdkeisnythiiyelieesqkqqekneqelleldkwanlwnwfdisnwlwyikifimivg
gliglrivfavlsvinrvrqgysplsfqtltpnprdpdrpgriegeggeqdrgrsirlvs
gflalawddlrnlclssyhqlrdfilivartvellghsslkglrlgweglkylgnlllyw
grelktsainlfdtiaivvagwtdrvievgqrlgrailniprrirqglerall

    Sequence, based on observed residues (ATOM records):
    >6ulcB (B:)
gflgtagstmgaasitltvqvrkllsgivqqqsnllraieaqqhllkltvwgikqlqarv
laverylrdqqllgiwgcsgklicttnvpwnsswsnksereiwenmtwlqwdkeisnyth
iiyelieesqkqqekneqelleld

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ulcC (C:)
mrvrgiqrncqhlwrwgtlilgmlmicsaaenlwvtvyygvpvwkdaettlfcasdakay
dtevhnvwathacvptdpnpqeiymenvteefnmwknnmveqmhtdiislwdqslkpcvq
ltplcvtldcsynitnnitnsitnssvnmreeikncsfnmttelrdknrkvyslfykldv
vqinngnnssnlyrlincntsaltqacpkvtfepipirycapagyailkcndkefngtgl
cknvstvqcthgirpvvstqlllngslaegkvmirsenitnnvkniivqlnetvtinctr
pnnntrksvrigpgqtfyatgdiigdirqahcnvsgsqwnralhqvvgqlreywnttiif
knssggdleitthsfncggeffycntsglfnsnwthndtasmkpndtitlpcrikqiinm
wqrvgqaiyappiqgvircesnitgliltrdgggninesqifrpgggdmrdnwrselyky
kvvrieplgvaptkakrrvverekr

    Sequence, based on observed residues (ATOM records):
    >6ulcC (C:)
enlwvtvyygvpvwkdaettlfcasdakaydtevhnvwathacvptdpnpqeiymenvte
efnmwknnmveqmhtdiislwdqslkpcvqltplcvtldcsynitnnitnsitnssvnmr
eeikncsfnmttelrdknrkvyslfykldvvqinngnnssnlyrlincntsaltqacpkv
tfepipirycapagyailkcndkefngtglcknvstvqcthgirpvvstqlllngslaeg
kvmirsenitnnvkniivqlnetvtinctrpnnntrksvrigpgqtfyatgdiigdirqa
hcnvsgsqwnralhqvvgqlreywnttiifknssggdleitthsfncggeffycntsglf
nsnwthndtasmkpndtitlpcrikqiinmwqrvgqaiyappiqgvircesnitgliltr
dgggninesqifrpgggdmrdnwrselykykvvrieplgvaptkakrrvve

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ulcD (D:)
avvelgavfigflgtagstmgaasitltvqvrkllsgivqqqsnllraieaqqhllkltv
wgikqlqarvlaverylrdqqllgiwgcsgklicttnvpwnsswsnksereiwenmtwlq
wdkeisnythiiyelieesqkqqekneqelleldkwanlwnwfdisnwlwyikifimivg
gliglrivfavlsvinrvrqgysplsfqtltpnprdpdrpgriegeggeqdrgrsirlvs
gflalawddlrnlclssyhqlrdfilivartvellghsslkglrlgweglkylgnlllyw
grelktsainlfdtiaivvagwtdrvievgqrlgrailniprrirqglerall

    Sequence, based on observed residues (ATOM records):
    >6ulcD (D:)
gflgtagstmgaasitltvqvrkllsgivqqqsnllraieaqqhllkltvwgikqlqarv
laverylrdqqllgiwgcsgklicttnvpwnsswsnksereiwenmtwlqwdkeisnyth
iiyelieesqkqqekneqelleld

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6ulcE (E:)
mrvrgiqrncqhlwrwgtlilgmlmicsaaenlwvtvyygvpvwkdaettlfcasdakay
dtevhnvwathacvptdpnpqeiymenvteefnmwknnmveqmhtdiislwdqslkpcvq
ltplcvtldcsynitnnitnsitnssvnmreeikncsfnmttelrdknrkvyslfykldv
vqinngnnssnlyrlincntsaltqacpkvtfepipirycapagyailkcndkefngtgl
cknvstvqcthgirpvvstqlllngslaegkvmirsenitnnvkniivqlnetvtinctr
pnnntrksvrigpgqtfyatgdiigdirqahcnvsgsqwnralhqvvgqlreywnttiif
knssggdleitthsfncggeffycntsglfnsnwthndtasmkpndtitlpcrikqiinm
wqrvgqaiyappiqgvircesnitgliltrdgggninesqifrpgggdmrdnwrselyky
kvvrieplgvaptkakrrvverekr

    Sequence, based on observed residues (ATOM records):
    >6ulcE (E:)
enlwvtvyygvpvwkdaettlfcasdakaydtevhnvwathacvptdpnpqeiymenvte
efnmwknnmveqmhtdiislwdqslkpcvqltplcvtldcsynitnnitnsitnssvnmr
eeikncsfnmttelrdknrkvyslfykldvvqinngnnssnlyrlincntsaltqacpkv
tfepipirycapagyailkcndkefngtglcknvstvqcthgirpvvstqlllngslaeg
kvmirsenitnnvkniivqlnetvtinctrpnnntrksvrigpgqtfyatgdiigdirqa
hcnvsgsqwnralhqvvgqlreywnttiifknssggdleitthsfncggeffycntsglf
nsnwthndtasmkpndtitlpcrikqiinmwqrvgqaiyappiqgvircesnitgliltr
dgggninesqifrpgggdmrdnwrselykykvvrieplgvaptkakrrvve

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6ulcF (F:)
avvelgavfigflgtagstmgaasitltvqvrkllsgivqqqsnllraieaqqhllkltv
wgikqlqarvlaverylrdqqllgiwgcsgklicttnvpwnsswsnksereiwenmtwlq
wdkeisnythiiyelieesqkqqekneqelleldkwanlwnwfdisnwlwyikifimivg
gliglrivfavlsvinrvrqgysplsfqtltpnprdpdrpgriegeggeqdrgrsirlvs
gflalawddlrnlclssyhqlrdfilivartvellghsslkglrlgweglkylgnlllyw
grelktsainlfdtiaivvagwtdrvievgqrlgrailniprrirqglerall

    Sequence, based on observed residues (ATOM records):
    >6ulcF (F:)
gflgtagstmgaasitltvqvrkllsgivqqqsnllraieaqqhllkltvwgikqlqarv
laverylrdqqllgiwgcsgklicttnvpwnsswsnksereiwenmtwlqwdkeisnyth
iiyelieesqkqqekneqelleld

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ulcH (H:)
mefglswvflvallrgvqcqeqlvesgggvvqpggslrlsclasgftfhkygmhwvrqap
gkglewvalisddgmrkyhsdsmwgrvtisrdnskntlylqfsslkvedtamffcareag
gpiwhddvkyydfndgyynyhymdvwgkgttvtvssastkgpsvfplapsskstsggtaa
lgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicn
vnhkpsntkvdkrvepkscdkasgggsawshpqfekgggsgggsggssawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6ulcH (H:)
qeqlvesgggvvqpggslrlsclasgftfhkygmhwvrqapgkglewvalisddgmrkyh
sdsmwgrvtisrdnskntlylqfsslkvedtamffcareaggpiwhddvkyydfndgyyn
yhymdvwgkgttvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswns
galtsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6ulcL (L:)
mawalllltlltqgtgswaqsaltqpasvsgspgqtitiscngtssdvggfdsvswyqqs
pgkapkvmvfdvshrpsgisnrfsgsksgntasltisglhiedegdyfcssltdrshrif
gggtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtvawkadsspvka
gvetttpskqsnnkyaassylsltpeqwkshksyscqvthegstvektvaptecsggsgg
hhhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6ulcL (L:)
qsaltqpasvsgspgqtitiscngtssdvggfdsvswyqqspgkapkvmvfdvshrpsgi
snrfsgsksgntasltisglhiedegdyfcssltdrshrifgggtkvtvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshksyscqvthegstvektvaptecs