PDB entry 6ul0

View 6ul0 on RCSB PDB site
Description: STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 4
Class: immune system
Keywords: agonist, sting (stimulator of interferon genes), transmembrane protein 173 (tmem173), immune system, immune system-inhibitor complex, immune system-agonist complex
Deposited on 2019-10-06, released 2020-08-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain
    Species: Homo sapiens [TaxId:9606]
    Gene: STING, LOC340061, hCG_1782396
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12306
      • linker (112)
    • Uniprot A0A2R3XZB7 (113-End)
      • engineered mutation (188)
      • engineered mutation (251)
    Domains in SCOPe 2.08: d6ul0a_
  • Heterogens: QBJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ul0A (A:)
mahhhhhhgsdsevnqeakpevkpevkpethinlkvsdgsseiffkikkttplrrlmeaf
akrqgkemdsltflydgieiqadqtpedldmedndiieahreqiggenlyfqsvahglaw
syyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnlsmadpnirf
ldklpqqtadragikdrvysnsiyellengqragtcvleyatplqtlfamsqysqagfsr
edrleqaklfcqtlediladapesqnncrliayqepaddssfslsqevlrhlrqeekeev

    Sequence, based on observed residues (ATOM records): (download) 
    >6ul0A (A:)
svahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnls
madpnirfldklpqqtadragikdrvysnsiyellengqragtcvleyatplqtlfamsq
ysqagfsredrleqaklfcqtlediladapesqnncrliayqepfslsqevlrhlrq