PDB entry 6ujp

View 6ujp on RCSB PDB site
Description: p-glycoprotein mutant-f979a and c952a-with bde100
Deposited on 2019-10-03, released 2020-05-27
The last revision was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 3.98 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent translocase ABCB1
    Species: Mus musculus [TaxId:10090]
    Gene: Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21447
      • engineered mutation (82)
      • engineered mutation (86)
      • engineered mutation (89)
      • engineered mutation (951)
      • engineered mutation (978)
  • Heterogens: 4C8

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ujpA (A:)
meleedlkgradknfskmgkkskkekkekkpavsvltmfryagwldrlymlvgtlaaiih
gvalplmmlifgdmtdsfasvgqvskqstqmseadkramfakleeemttyayyytgigag
vlivayiqvsfwclaagrqihkirqkffhaimnqeigwfdvhdvgelntrltddvskine
gigdkigmffqamatffggfiigftrgwkltlvilaispvlglsagiwakilssftdkel
hayakagavaeevlaairtviafggqkkelerynnnleeakrlgikkaitanismgaafl
liyasyalafwygtslviskeysigqvltvffsvligafsvgqaspnieafanargaaye
vfkiidnkpsidsfsksghkpdniqgnlefknihfsypsrkevqilkglnlkvksgqtva
lvgnsgcgksttvqlmqrlydpldgmvsidgqdirtinvrylreiigvvsqepvlfatti
aenirygredvtmdeiekavkeanaydfimklphqfdtlvgergaqlsggqkqriaiara
lvrnpkillldeatsaldteseavvqaaldkaregrttiviahrlstvrnadviagfdgg
viveqgnhdelmrekgiyfklvmtqtagneielgneackskdeidnldmsskdsgsslir
rrstrksicgphdqdrklstkealdedvppasfwrilklnstewpyfvvgifcaiinggl
qpafsvifskvvgvftnggppetqrqnsnlfsllflilgiisfitfflqgftfgkageil
tkrlrymvfksmlrqdvswfddpknttgalttrlandaaqvkgatgsrlavifqnianlg
tgiiisliygwqltllllaivpiiaiagvvemkmlsgqalkdkkelegsgkiateaienf
rtvvsltreqkfetmyaqslqipyrnamkkahvfgitfsftqammyfsyaaafrfgaylv
tqqlmtfenvllvfsaivagamavgqvssfapdyakatvsashiiriiektpeidsystq
glkpnmlegnvqfsgvvfnyptrpsipvlqglslevkkgqtlalvgssgcgkstvvqlle
rfydpmagsvfldgkeikqlnvqwlraqlgivsqepilfdcsiaeniaygdnsrvvsyee
ivraakeanihqfidslpdkyntrvgdkgtqlsggqkqriaiaralvrqphillldeats
aldtesekvvqealdkaregrtciviahrlstiqnadlivviqngkvkehgthqqllaqk
giyfsmvsvqagakrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6ujpA (A:)
kpavsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgdmtdsfasvgqvskqst
qmseadkramfakleeemttyayyytgigagvlivayiqvsfwclaagrqihkirqkffh
aimnqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrgwk
ltlvilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqkke
lerynnnleeakrlgikkaitanismgaaflliyasyalafwygtslviskeysigqvlt
vffsvligafsvgqaspnieafanargaayevfkiidnkpsidsfsksghkpdniqgnle
fknihfsypsrkevqilkglnlkvksgqtvalvgnsgcgksttvqlmqrlydpldgmvsi
dgqdirtinvrylreiigvvsqepvlfattiaenirygredvtmdeiekavkeanaydfi
mklphqfdtlvgergaqlsggqkqriaiaralvrnpkillldeatsaldteseavvqaal
dkaregrttiviahrlstvrnadviagfdggviveqgnhdelmrekgiyfklvmtqtppa
sfwrilklnstewpyfvvgifcaiingglqpafsvifskvvgvftnggppetqrqnsnlf
sllflilgiisfitfflqgftfgkageiltkrlrymvfksmlrqdvswfddpknttgalt
trlandaaqvkgatgsrlavifqnianlgtgiiisliygwqltllllaivpiiaiagvve
mkmlsgqalkdkkelegsgkiateaienfrtvvsltreqkfetmyaqslqipyrnamkka
hvfgitfsftqammyfsyaaafrfgaylvtqqlmtfenvllvfsaivagamavgqvssfa
pdyakatvsashiiriiektpeidsystqglkpnmlegnvqfsgvvfnyptrpsipvlqg
lslevkkgqtlalvgssgcgkstvvqllerfydpmagsvfldgkeikqlnvqwlraqlgi
vsqepilfdcsiaeniaygdnsrvvsyeeivraakeanihqfidslpdkyntrvgdkgtq
lsggqkqriaiaralvrqphillldeatsaldtesekvvqealdkaregrtciviahrls
tiqnadlivviqngkvkehgthqqllaqkgiyfsmvsvqaga