PDB entry 6uir

View 6uir on RCSB PDB site
Description: hiv-1 m184v reverse transcriptase-dna complex with (-)-ftc-tp
Deposited on 2019-10-01, released 2019-12-25
The last revision was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: XRAY
Resolution: 2.64 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: p66 Reverse transcriptase/RNaseH
    Species: Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585 (12-End)
      • engineered mutation (195)
      • engineered mutation (269)
      • engineered mutation (291)
  • Chain 'B':
    Compound: p51 Reverse transcriptase/RNaseH
    Species: Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585
      • engineered mutation (183)
      • engineered mutation (279)
  • Chain 'P':
    Compound: Primer DNA
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
  • Chain 'T':
    Compound: Template DNA
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
  • Heterogens: 1RY, SO4, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6uirA (A:)
mgsshhhhhhsspispietvpvklkpgmdgpkvkqwplteekikalveictemekegkis
kigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtv
ldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkil
epfrkqnpdiviyqyvddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppfl
wmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtka
lteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfkn
lktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqa
twipewefvntpplvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvt
ltdttnqktelqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikk
ekvylawvpahkgiggneqvdklvsagirkvl

    Sequence, based on observed residues (ATOM records):
    >6uirA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqyvddlyvgsd
leigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdsw
tvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilke
pvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteav
qkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqleke
pivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelqaiylalqdsgle
vnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvdklv
sagi

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6uirB (B:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqyvddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records):
    >6uirB (B:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdpaglkkkksvtvldvgdayfsvpldedfrkytaftips
innetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqyvddlyvgsdle
igqhrtkieelrqhllrwgelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypg
ikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqg
qgqwtyqiyqepfknlktgkyarahtndvkqlteavqkittesiviwgktpkfklpiqke
twetwwteywqatwipewefvntpplvklwyq

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.