PDB entry 6uhd

View 6uhd on RCSB PDB site
Description: crystal structure of human histone acetyltransferase 1 (hat1) in complex with isobutyryl-coa and k12a mutant variant of histone peptide h4
Deposited on 2019-09-27, released 2019-10-16
Made obsolete by 6vo5 on 2020-03-11

The last revision was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase type B catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: HAT1, KAT1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone acetyltransferase type B catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: HAT1, KAT1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14929 (2-End)
      • expression tag (0-1)
  • Chain 'C':
    Compound: histone h4
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62805
      • engineered mutation (11)
  • Chain 'D':
    Compound: histone h4
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62805
      • engineered mutation (11)
  • Heterogens: CO6, ACT, GOL, SO4, UNX, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6uhdA (A:)
gskklaeykcntntaielklvrfpedlendirtffpeythqlfgddetafgykglkilly
yiagslstmfrveyaskvdenfdcveaddvegkirqiippgfctntndflsllekevdfk
pfgtllhtysvlsptggenftfqiykadmtcrgfreyherlqtflmwfietasfidvdde
rwhyflvfekynkdgatlfatvgymtvynyyvypdktrprvsqmliltpfqgqghgaqll
etvhryytefptvlditaedpsksyvklrdfvlvklcqdlpcfsreklmqgfnedmaiea
qqkfkinkqharrvyeilrllvtd

    Sequence, based on observed residues (ATOM records):
    >6uhdA (A:)
kklaeykcntntaielklvrfpedlendirtffpeythqlfgddetafgykglkillyyi
agslstmfrveyaskvdenfdcveaddvegkirqiippgfctntndflsllekevdfkpf
gtllhtysvlsptggenftfqiykadmtcrgfreyherlqtflmwfietasfidvdderw
hyflvfekynkdgatlfatvgymtvynyyvypdktrprvsqmliltpfqgqghgaqllet
vhryytefptvlditaedpsksyvklrdfvlvklcqdlpcfsreklmqgfnedmaieaqq
kfkinkqharrvyeilrllvtd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6uhdB (B:)
gskklaeykcntntaielklvrfpedlendirtffpeythqlfgddetafgykglkilly
yiagslstmfrveyaskvdenfdcveaddvegkirqiippgfctntndflsllekevdfk
pfgtllhtysvlsptggenftfqiykadmtcrgfreyherlqtflmwfietasfidvdde
rwhyflvfekynkdgatlfatvgymtvynyyvypdktrprvsqmliltpfqgqghgaqll
etvhryytefptvlditaedpsksyvklrdfvlvklcqdlpcfsreklmqgfnedmaiea
qqkfkinkqharrvyeilrllvtd

    Sequence, based on observed residues (ATOM records):
    >6uhdB (B:)
gskklaeykcntntaielklvrfpedlendirtffpeythqlfgddetafgykglkilly
yiagslstmfrveyaskvdenfdcveaddvegkirqiippgfctntndflsllekevdfk
pfgtllhtysvlenftfqiykadmtcrgfreyherlqtflmwfietasfidvdderwhyf
lvfekynkdgatlfatvgymtvynyyvypdktrprvsqmliltpfqgqghgaqlletvhr
yytefptvlditaedpsksyvklrdfvlvklcqdlpcfsreklmqgfnedmaieaqqkfk
inkqharrvyeilrllvt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6uhdC (C:)
sgrgkggkglgaggakrhrk

    Sequence, based on observed residues (ATOM records):
    >6uhdC (C:)
kggkglgaggakrhr

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6uhdD (D:)
sgrgkggkglgaggakrhrk

    Sequence, based on observed residues (ATOM records):
    >6uhdD (D:)
ggkglgaggakrhr