PDB entry 6ue6

View 6ue6 on RCSB PDB site
Description: pwwp1 domain of nsd2 in complex with mr837
Deposited on 2017-09-27, released 2019-11-13
The last revision was dated 2021-04-21, with a file datestamp of 2021-04-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Histone-lysine N-methyltransferase NSD2
    Species: Homo sapiens [TaxId:9606]
    Gene: NSD2, KIAA1090, MMSET, TRX5, WHSC1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: Q5D, UNX

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ue6A (A:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6A (A:)
kdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkksarqyhvqffgdaperawi
fekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqaeeaasms
veerkakftfly

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ue6B (B:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6B (B:)
llkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgdaperawi
fekslvafegegqfeklcqesakqaikllkpisgklraqwemgivqaeeaasmsveerka
kftf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ue6C (C:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6C (C:)
llkynvgdlvwskvsgypwwpcmvsadpllhsytklkgsarqyhvqffgdaperawifek
slvafegegqfekisgklraqwemgivqaeeaasmsveerkakftfl

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ue6D (D:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6D (D:)
lkynvgdlvwskvsgypwwpcmvsadpllhsytklkgarqyhvqffgdaperawifeksl
vafegegqfeklcqesakqakikllkpisgklraqwemgivqaeeaasmsveerkakftf

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6ue6E (E:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6E (E:)
llkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqsarqyhvqffgdaperawife
kslvafegegqfeklcqesakqakaekikllkpisgklraqwemgivqaeeaasmsveer
kakftf

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6ue6F (F:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6F (F:)
llkynvgdlvwskvsgypwwpcmvsadpllhsytklkarqyhvqffgdaperawifeksl
vafegegqfeklcqesgklraqwemgivqaeeaasmsveerkakftfl

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6ue6G (G:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6G (G:)
hllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgsarqyhvqffgdaperawife
kslvafegegqfeklcqesakqappisgklraqwemgivqaeeaasmsveerkakftfly
v

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ue6H (H:)
ggrdkdhllkynvgdlvwskvsgypwwpcmvsadpllhsytklkgqkksarqyhvqffgd
aperawifekslvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqa
eeaasmsveerkakftflyvg

    Sequence, based on observed residues (ATOM records):
    >6ue6H (H:)
hllkynvgdlvwskvsgypwwpcmvsadpllhsytklkarqyhvqffgdaperawifeks
lvafegegqfeklcqesakqaptkaekikllkpisgklraqwemgivqaeeaasmsveer
kakftfly