PDB entry 6ue3

View 6ue3 on RCSB PDB site
Description: Crystal structure of HCV NS3/4A D168A protease in complex with PC (JZ01-15)
Class: antiviral protein
Keywords: Drug Resistance, Protease inhibitor, HYDROLASE-HYDROLASE Inhibitor complex, HYDROLASE, VIRAL PROTEIN, ANTIVIRAL PROTEIN
Deposited on 2019-09-20, released 2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-16, with a file datestamp of 2020-09-11.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NS3 protease
    Species: Hepacivirus C [TaxId:11103]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UE3
    Domains in SCOPe 2.08: d6ue3a1, d6ue3a2
  • Heterogens: 9H4, ZN, EDO, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ue3A (A:)
hmasmkkkgsvvivgrinlsgdtayaqqtrgeegcqetsqtgrdknqvegevqivstatq
tflatsingvlwtvyhgagtrtiaspkgpvtqmytnvdkdlvgwqapqgsrsltpctcgs
sdlylvtrhadvipvrrrgdsrgsllsprpisylkgssggpllcpaghavgifraavstr
gvakavafipveslettmrs

    Sequence, based on observed residues (ATOM records): (download) 
    >6ue3A (A:)
masmkkkgsvvivgrinlsgdtayaqqtrgeegcqetsqtgrdknqvegevqivstatqt
flatsingvlwtvyhgagtrtiaspkgpvtqmytnvdkdlvgwqapqgsrsltpctcgss
dlylvtrhadvipvrrrgdsrgsllsprpisylkgssggpllcpaghavgifraavstrg
vakavafipveslettm