PDB entry 6udm

View 6udm on RCSB PDB site
Description: Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2726
Class: oxidoreductase
Keywords: CYP1A1, P450, OXIDOREDUCTASE, Duocarmycin
Deposited on 2019-09-19, released 2020-09-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 3.08 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6udma_
  • Chain 'B':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6udmb_
  • Chain 'C':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6udmc_
  • Chain 'D':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6udmd_
  • Heterogens: Q4P, HEM, CPS

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6udmA (A:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udmA (A:)
lknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqal
vrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpassts
cyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqells
lvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfekg
hirditdsliehcqeklsdekiinivldlfgagfdtvttaiswslmylvmnprvqrkiqe
eldtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdtslkgfyipkgr
cvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkrkcigetiarw
evflflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6udmB (B:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udmB (B:)
lknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqal
vrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpassts
cyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqells
lvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfekg
hirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttaiswslmylvmn
prvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdtsl
kgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkrk
cigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6udmC (C:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udmC (C:)
lknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqal
vrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpassts
cyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqells
lvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfekg
hirditdsliehcqekqlsdekiinivldlfgagfdtvttaiswslmylvmnprvqrkiq
eeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdtslkgfyipkg
rcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkrkcigetiar
wevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6udmD (D:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udmD (D:)
lknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqal
vrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpassts
cyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqells
lvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfekg
hirditdsliehcqlsdekiinivldlfgagfdtvttaiswslmylvmnprvqrkiqeel
dtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdtslkgfyipkgrcv
fvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkrkcigetiarwev
flflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs