PDB entry 6udl

View 6udl on RCSB PDB site
Description: Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2700
Class: oxidoreductase
Keywords: CYP1A1, P450, OXIDOREDUCTASE, Duocarmycin
Deposited on 2019-09-19, released 2020-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6udla_
  • Chain 'B':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6udlb_
  • Chain 'C':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6udlc_
  • Chain 'D':
    Compound: Cytochrome P450 1A1
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP1A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6udld_
  • Heterogens: Q4M, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6udlA (A:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udlA (A:)
glknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqa
lvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpasst
scyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqell
slvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfek
ghirditdsliehcqekqlsdekiinivldlfgagfdtvttaiswslmylvmnprvqrki
qeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdtslkgfyipk
grcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkrkcigetia
rwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6udlB (B:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udlB (B:)
glknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqa
lvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpasst
scyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqell
slvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfek
ghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttaiswslmylvm
nprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdts
lkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkr
kcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6udlC (C:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udlC (C:)
glknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqa
lvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpasst
scyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqell
slvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfek
ghirditdsliehcqlsdekiinivldlfgagfdtvttaiswslmylvmnprvqrkiqee
ldtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdtslkgfyipkgrc
vfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkrkcigetiarwe
vflflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6udlD (D:)
makktsskglknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvls
gldtirqalvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsi
asdpasstscyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrry
dhnhqellslvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvk
ehyktfekghirditdsliehcqekqldenanvqlsdekiinivldlfgagfdtvttais
wslmylvmnprvqrkiqeeldtvigrsrrprlsdrshlpymeafiletfrhssfvpftip
hsttrdtslkgfyipkgrcvfvnqwqinhdqklwvnpseflperfltpdgaidkvlsekv
iifgmgkrkcigetiarwevflflaillqrvefsvplgvkvdmtpiygltmkhaccehfq
mqlrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6udlD (D:)
glknppgpwgwplighmltlgknphlalsrmsqqygdvlqirigstpvvvlsgldtirqa
lvrqgddfkgrpdlytftlisngqsmsfspdsgpvwaarrrlaqnglksfsiasdpasst
scyleehvskeaevlistlqelmagpghfnpyryvvvsvtnvicaicfgrrydhnhqell
slvnlnnnfgevvgsgnpadfipilrylpnpslnafkdlnekfysfmqkmvkehyktfek
ghirditdsliehclsdekiinivldlfgagfdtvttaiswslmylvmnprvqrkiqeel
dtvigrsrrprlsdrshlpymeafiletfrhssfvpftiphsttrdtslkgfyipkgrcv
fvnqwqinhdqklwvnpseflperfltpdgaidkvlsekviifgmgkrkcigetiarwev
flflaillqrvefsvplgvkvdmtpiygltmkhaccehfqmqlrs