PDB entry 6uc6

View 6uc6 on RCSB PDB site
Description: Crystal structure of BoNT/B receptor-binding domain in complex with VHH JLI-H11
Class: hydrolase/antitoxin
Keywords: Botulinum neurotoxin (BoNT), VHH, receptor-binding domain, TOXIN, ANTITOXIN, HYDROLASE-ANTITOXIN complex
Deposited on 2019-09-15, released 2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: botulinum neurotoxin type b
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6uc6a1, d6uc6a2
  • Chain 'B':
    Compound: botulinum neurotoxin type b
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6uc6b1, d6uc6b2
  • Chain 'C':
    Compound: jli-h11
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UC6
    Domains in SCOPe 2.08: d6uc6c_
  • Chain 'D':
    Compound: jli-h11
    Species: Vicugna pacos [TaxId:30538]
    Database cross-references and differences (RAF-indexed):
    • PDB 6UC6
    Domains in SCOPe 2.08: d6uc6d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6uc6A (A:)
gplgseilnniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanskirvtq
nqniifnsvfldfsvsfwiripkykndgiqnyihneytiincmknnsgwkisirgnriiw
tlidingktksvffeynirediseyinrwffvtitnnlnnakiyingklesntdikdire
viangeiifkldgdidrtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwgnplm
ynkeyymfnagnknsyiklkkdspvgeiltrskynqnskyinyrdlyigekfiirrksns
qsinddivrkedyiyldffnlnqewrvytykyfkkeeeklflapisdsdefyntiqikey
deqptyscqllfkkdeestdeigligihrfyesgivfeeykdyfciskwylkevkrkpyn
lklgcnwqfipkdegwte

    Sequence, based on observed residues (ATOM records): (download) 
    >6uc6A (A:)
nniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanskirvtqnqnidfsv
sfwiripkykndgiqnyihneytiincmknnsgwkisirgnriiwtlidingktksvffe
ynirediseyinrwffvtitnnlnnakiyingklesntdikdireviangeiifkldgdi
drtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwgnplmynkeyymfnagnkns
yiklkkdspvgeiltrskynqnskyinyrdlyigekfiirrksnnddivrkedyiyldff
nlnqewrvytykyfkkeeeklflapisdsdefyntiqikeydeqptyscqllfkkdeest
deigligihrfyeseykdyfciskwylkevkrkpynlklgcnwqfipkdegwte

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6uc6B (B:)
gplgseilnniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanskirvtq
nqniifnsvfldfsvsfwiripkykndgiqnyihneytiincmknnsgwkisirgnriiw
tlidingktksvffeynirediseyinrwffvtitnnlnnakiyingklesntdikdire
viangeiifkldgdidrtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwgnplm
ynkeyymfnagnknsyiklkkdspvgeiltrskynqnskyinyrdlyigekfiirrksns
qsinddivrkedyiyldffnlnqewrvytykyfkkeeeklflapisdsdefyntiqikey
deqptyscqllfkkdeestdeigligihrfyesgivfeeykdyfciskwylkevkrkpyn
lklgcnwqfipkdegwte

    Sequence, based on observed residues (ATOM records): (download) 
    >6uc6B (B:)
nniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanskirvtqnqnivfld
fsvsfwiripkykndgiqnyihneytiincmknnsgwkisirgnriiwtlidingktksv
ffeynirediseyinrwffvtitnnlnnakiyingklesntdikdireviangeiifkld
gdidrtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwgnplmynkeyymfnagn
knsyiklkkdspvgeiltrskynqnskyinyrdlyigekfiirrksddivrkedyiyldf
fnlnqewrvytykyfkkeeeklflapisdsdefyntiqikeydeqptyscqllfkkdees
tdeigligihrfyykdyfciskwylkevkrkpynlklgcnwqfipkdegwte

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6uc6C (C:)
mhhhhhhmasmtggqqmgrgsqvqlvesggglvqpgeslrlscgasgmsldyyaiawyrq
apgkeregvscisvsgssaqyldsvrgrfiiskdntkstaylqmnslkpedtavyycaal
adcagyasltfdfdswgqgtqvavssahhsedps

    Sequence, based on observed residues (ATOM records): (download) 
    >6uc6C (C:)
vqlvesggglvqpgeslrlscgasgmsldyyaiawyrqapgkeregvscisvsgssaqyl
dsvrgrfiiskdntkstaylqmnslkpedtavyycaaladcagyasltfdfdswgqgtqv
avssah

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6uc6D (D:)
mhhhhhhmasmtggqqmgrgsqvqlvesggglvqpgeslrlscgasgmsldyyaiawyrq
apgkeregvscisvsgssaqyldsvrgrfiiskdntkstaylqmnslkpedtavyycaal
adcagyasltfdfdswgqgtqvavssahhsedps

    Sequence, based on observed residues (ATOM records): (download) 
    >6uc6D (D:)
sqvqlvesggglvqpgeslrlscgasgmsldyyaiawyrqapgkeregvscisvsgssaq
yldsvrgrfiiskdntkstaylqmnslkpedtavyycaaladcagyasltfdfdswgqgt
qvavssah