PDB entry 6uc0

View 6uc0 on RCSB PDB site
Description: isolated s3d-cofilin bound to an actin filament
Deposited on 2019-09-13, released 2020-01-01
The last revision was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: EM
Resolution: 7.5 Å
R-factor: N/A
AEROSPACI score: -0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: cofilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CFL1, CFL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23528 (Start-165)
      • engineered mutation (2)
  • Heterogens: MG, ADP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6uc0A (A:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6uc0A (A:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
agpsivhrkc

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6uc0B (B:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6uc0B (B:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
agpsivhrkc

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6uc0C (C:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6uc0C (C:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
agpsivhrkc

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6uc0D (D:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6uc0D (D:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
agpsivhrkc

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6uc0E (E:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6uc0E (E:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
agpsivhrkc

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6uc0F (F:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6uc0F (F:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
agpsivhrkc

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6uc0G (G:)
mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
kqeydeagpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6uc0G (G:)
ttalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgi
ltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimf
etfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrd
ltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpd
gqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggtt
mypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeyde
agpsivhrkc

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6uc0I (I:)
madgvavsdgvikvfndmkvrksstpeevkkrkkavlfclsedkkniileegkeilvgdv
gqtvddpyatfvkmlpdkdcryalydatyetkeskkedlvfifwapesaplkskmiyass
kdaikkkltgikhelqancyeevkdrctlaeklggsavislegkpl

    Sequence, based on observed residues (ATOM records):
    >6uc0I (I:)
dgvavsdgvikvfndmkvrksstpeevkkrkkavlfclsedkkniileegkeilvgdvgq
tvddpyatfvkmlpdkdcryalydatyetkeskkedlvfifwapesaplkskmiyasskd
aikkkltgikhelqancyeevkdrctlaeklggsavislegkpl