PDB entry 6u62

View 6u62 on RCSB PDB site
Description: Raptor-Rag-Ragulator complex
Class: signaling protein
Keywords: signaling complex, GTPase, lysosome, SIGNALING PROTEIN
Deposited on 2019-08-29, released 2019-10-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-10-30, with a file datestamp of 2019-10-25.
Experiment type: EM
Resolution: 3.18 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: regulatory-associated protein of mtor
  Species: Homo sapiens [TaxId:9606]
  Gene: RPTOR, KIAA1303, RAPTOR
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q8N122
• Chain 'B':
  Compound: Ras-related GTP-binding protein A
  Species: Homo sapiens [TaxId:9606]
  Gene: RRAGA
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q7L523
• Chain 'C':
  Compound: Ras-related GTP-binding protein C
  Species: Homo sapiens [TaxId:9606]
  Gene: RRAGC
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9HB90
    • engineered mutation (75)
• Chain 'D':
  Compound: Ragulator complex protein LAMTOR1
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR1, C11orf59, PDRO, PP7157
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q6IAA8 (Start-157)
• Chain 'E':
  Compound: Ragulator complex protein LAMTOR2
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR2, MAPBPIP, ROBLD3, HSPC003
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9Y2Q5 (0-End)
  Domains in SCOPe 2.07: d6u62e_
• Chain 'F':
  Compound: Ragulator complex protein LAMTOR3
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR3, MAP2K1IP1, MAPKSP1, PRO2783
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9UHA4
  Domains in SCOPe 2.07: d6u62f_
• Chain 'G':
  Compound: Ragulator complex protein LAMTOR4
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR4, C7orf59
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q0VGL1
• Chain 'H':
  Compound: Ragulator complex protein LAMTOR5
  Species: Homo sapiens [TaxId:9606]
  Gene: LAMTOR5, HBXIP, XIP
  Database cross-references and differences (RAF-indexed):
  • Uniprot O43504 (0-End)
• Heterogens: GDP, GTP, MG

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  Sequence, based on SEQRES records: (download)
  

  >6u62E (E:)
  mlrpkaltqvlsqantggvqstlllnnegsllaysgygdtdarvtaaiasniwaaydrng
  nqafnednlkfilmdcmegrvaitrvanlllcmyaketvgfgmlkakaqalvqyleeplt
  qvaas
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6u62E (E:)
  mlrpkaltqvlsqantggvqstlllnnegsllaysgygdtdarvtaaiasniwaaydrng
  nqafnednlkfilmdcmegrvaitrvanlllcmyaketvgfgmlkakaqalvqyleeplt
  qvaa
  

  
  
• Chain 'F':
  Sequence, based on SEQRES records: (download)
  

  >6u62F (F:)
  maddlkrflykklpsveglhaivvsdrdgvpvikvandnapehalrpgflstfalatdqg
  sklglsknksiicyyntyqvvqfnrlplvvsfiasssantglivslekelaplfeelrqv
  vevsenlyfqgssgwshpqfekgggsgggsgggswshpqfek
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6u62F (F:)
  ddlkrflykklpsveglhaivvsdrdgvpvikvandnapehalrpgflstfalatdqgsk
  lglsknksiicyyntyqvvqfnrlplvvsfiasssantglivslekelaplfeelrqvve
  

  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  No sequence available.