PDB entry 6u3u

View 6u3u on RCSB PDB site
Description: Crystal Structure of Shiga Toxin 2K
Class: toxin
Keywords: Shiga Toxin, AB5 Toxin, Toxoid, TOXIN
Deposited on 2019-08-22, released 2020-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-01, with a file datestamp of 2020-06-26.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Shiga toxin 2K subunit A
    Species: Escherichia coli [TaxId:562]
    Gene: STX2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot L0I969 (0-296)
      • engineered mutation (166)
    Domains in SCOPe 2.08: d6u3ua_
  • Chain 'B':
    Compound: Shiga toxin 2K subunit A
    Species: Escherichia coli [TaxId:562]
    Gene: STX2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot L0I969 (0-296)
      • engineered mutation (166)
    Domains in SCOPe 2.08: d6u3ub_
  • Chain 'C':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3uc_
  • Chain 'D':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3ud_
  • Chain 'E':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3ue_
  • Chain 'F':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3uf_
  • Chain 'G':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3ug_
  • Chain 'H':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3uh_
  • Chain 'I':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3ui_
  • Chain 'J':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3uj_
  • Chain 'K':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3uk_
  • Chain 'L':
    Compound: Shiga toxin 2K subunit B
    Species: Escherichia coli [TaxId:562]
    Gene: vtx2B, stx2B, stx2B_2, BvCmsKKP036_03423, BvCmsNSP045_04912
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3ul_
  • Heterogens: EPE, EDO, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6u3uA (A:)
qeftidfstqqsyvsslnsirtaistplehisqgatsvsvinhtppgsyisvgirgldvy
qahfdhlrliieqnnlyvagfvntatntfyrfsdfahislpgvttismttdssyttlqrv
aalersgmqisrhslvssylalmefsgntmtreasravlrfvtvtaqalrfrqiqrefrq
alsetapvytmtpedvdltlnwgrisnvlpeyrgedgvrvgrisfnnisailgtvaviln
chhqgarsvravneesqpecqitgdrpvikinntlwesntaaaflnrksqslyttge

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3uA (A:)
qeftidfstqqsyvsslnsirtaistplehisqgatsvsvinhtppgsyisvgirgldvy
qahfdhlrliieqnnlyvagfvntatntfyrfsdfahislpgvttismttdssyttlqrv
aalersgmqisrhslvssylalmefsgntmtreasravlrfvtvtaqalrfrqiqrefrq
alsetapvytmtpedvdltlnwgrisnvlpeyrgedgvrvgrisfnnisailgtvaviln
chhpecqitgdrpvikinntlwesntaaaflnrksqslyttge

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6u3uB (B:)
qeftidfstqqsyvsslnsirtaistplehisqgatsvsvinhtppgsyisvgirgldvy
qahfdhlrliieqnnlyvagfvntatntfyrfsdfahislpgvttismttdssyttlqrv
aalersgmqisrhslvssylalmefsgntmtreasravlrfvtvtaqalrfrqiqrefrq
alsetapvytmtpedvdltlnwgrisnvlpeyrgedgvrvgrisfnnisailgtvaviln
chhqgarsvravneesqpecqitgdrpvikinntlwesntaaaflnrksqslyttge

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3uB (B:)
qeftidfstqqsyvsslnsirtaistplehisqgatsvsvinhtppgsyisvgirgldvy
qahfdhlrliieqnnlyvagfvntatntfyrfsdfahislpgvttismttdssyttlqrv
aalersgmqisrhslvssylalmefsgntmtreasravlrfvtvtaqalrfrqiqrefrq
alsetapvytmtpedvdltlnwgrisnvlpeyrgedgvrvgrisfnnisailgtvaviln
chqpecqitgdrpvikinntlwesntaaaflnrksqslyttge

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uC (C:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uD (D:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uE (E:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uF (F:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uG (G:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uH (H:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uI (I:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uJ (J:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uK (K:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6u3uL (L:)
adcakgkiefskynendtftvkvagkeywtnrwnlqpllqsaqltgmtvtiksstcasgs
gfaevqfnnd