PDB entry 6u3o

View 6u3o on RCSB PDB site
Description: JR51 DQ2-p.aeru-alpha2a complex
Class: immune system
Keywords: Immune Complex, Celiac disease, Gliadin epitope, TCR cross-reactivity, IMMUNE SYSTEM
Deposited on 2019-08-22, released 2019-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.74 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-CELL RECEPTOR, JR5.1 alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3O (0-End)
    Domains in SCOPe 2.08: d6u3oa1, d6u3oa2
  • Chain 'B':
    Compound: T-CELL RECEPTOR, JR5.1 beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3O
    Domains in SCOPe 2.08: d6u3ob1, d6u3ob2
  • Chain 'C':
    Compound: MHC class II HLA-DQ-alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O19705 (Start-182)
      • conflict (46)
    Domains in SCOPe 2.08: d6u3oc1, d6u3oc2
  • Chain 'D':
    Compound: MHC class II HLA-DQ-beta-1
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3od1, d6u3od2
  • Chain 'E':
    Compound: MHC class II HLA-DQ-alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O19705 (Start-182)
      • conflict (46)
    Domains in SCOPe 2.08: d6u3oe1, d6u3oe2
  • Chain 'F':
    Compound: MHC class II HLA-DQ-beta-1
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DQB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6u3of1, d6u3of2
  • Chain 'G':
    Compound: T-CELL RECEPTOR, JR5.1 alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3O (0-End)
    Domains in SCOPe 2.08: d6u3og1, d6u3og2
  • Chain 'H':
    Compound: T-CELL RECEPTOR, JR5.1 beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3O
    Domains in SCOPe 2.08: d6u3oh1, d6u3oh2
  • Chain 'I':
    Compound: peptide
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3O (0-End)
  • Chain 'J':
    Compound: peptide
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U3O (0-End)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6u3oA (A:)
mkttqppsmdcaegraanlpcnhstisgneyvywyrqihsqgpqyiihglknnetnemas
liitedrksstlilphatlrdtavyyciafqgaqklvfgqgtrltinpniqnpdpavyql
rdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfa
canafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oA (A:)
mkttqppsmdcaegraanlpcnhstisgneyvywyrqihsqgpqyiihglknnetnemas
liitedrksstlilphatlrdtavyyciafqgaqklvfgqgtrltinpniqnpdpavyql
rdsdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfacan
afnnsiipedtffp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6u3oB (B:)
mgvsqspsnkvtekgkdvelrcdpisghtalywyrqslgqglefliyfqgnsapdksglp
sdrfsaertggsvstltiqrtqqedsavylcassfralaadtqyfgpgtrltvledlknv
fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeq
palndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
grad

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oB (B:)
gvsqspsnkvtekgkdvelrcdpisghtalywyrqslgqglefliyfqgnsapdksglps
drfsaertggsvstltiqrtqqedsavylcassfralaadtqyfgpgtrltvledlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
ra

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6u3oC (C:)
edivadhvasygvnlyqsygpsgqythefdgdeqfyvdlgrketvwslpvlrqfrfdpqf
altniavlkhnlnslikrsnstaatnevpevtvfskspvtlgqpniliclvdnifppvvn
itwlsnghsvtegvsetsflsksdhsffkisyltllpsaeesydckvehwgldkpllkhw
epetsgddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oC (C:)
ivadhvasygvnlyqsygpsgqythefdgdeqfyvdlgrketvwslpvlrqfrfdpqfal
tniavlkhnlnslikrsnstaatnevpevtvfskspvtlgqpniliclvdnifppvvnit
wlsnghsvtegvsetsflsksdhsffkisyltllpsaeesydckvehwgldkpllkhwep
e

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6u3oD (D:)
ggsgasrdspedfvyqfkgmcyftngtervrlvsrsiynreeivrfdsdvgefravtllg
lpaaeywnsqkdilerkraavdrvcrhnyqlelrttlqrrveptvtispsrtealnhhnl
lvcsvtdfypaqikvrwfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytch
vehpslqspitvewraqstggddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oD (D:)
spedfvyqfkgmcyftngtervrlvsrsiynreeivrfdsdvgefravtllglpaaeywn
sqkdilerkraavdrvcrhnyqlelrttlqrrveptvtispshnllvcsvtdfypaqikv
rwfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytchvehpslqspitvewr
a

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6u3oE (E:)
edivadhvasygvnlyqsygpsgqythefdgdeqfyvdlgrketvwslpvlrqfrfdpqf
altniavlkhnlnslikrsnstaatnevpevtvfskspvtlgqpniliclvdnifppvvn
itwlsnghsvtegvsetsflsksdhsffkisyltllpsaeesydckvehwgldkpllkhw
epetsgddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oE (E:)
ivadhvasygvnlyqsygpsgqythefdgdeqfyvdlgrketvwslpvlrqfrfdpqfal
tniavlkhnlnslikrsnstaatnevpevtvfskspvtlgqpniliclvdnifppvvnit
wlsnghsvtegvsetsflsksdhsffkisyltllpsaeesydckvehwgldkpllkhwep
e

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6u3oF (F:)
ggsgasrdspedfvyqfkgmcyftngtervrlvsrsiynreeivrfdsdvgefravtllg
lpaaeywnsqkdilerkraavdrvcrhnyqlelrttlqrrveptvtispsrtealnhhnl
lvcsvtdfypaqikvrwfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytch
vehpslqspitvewraqstggddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oF (F:)
spedfvyqfkgmcyftngtervrlvsrsiynreeivrfdsdvgefravtllglpaaeywn
sqkdilerkraavdrvcrhnyqlelrttlqrrveptvtispshnllvcsvtdfypaqikv
rwfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytchvehpslqspitvewr
a

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6u3oG (G:)
mkttqppsmdcaegraanlpcnhstisgneyvywyrqihsqgpqyiihglknnetnemas
liitedrksstlilphatlrdtavyyciafqgaqklvfgqgtrltinpniqnpdpavyql
rdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfa
canafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oG (G:)
mkttqppsmdcaegraanlpcnhstisgneyvywyrqihsqgpqyiihglknnetnemas
liitedrksstlilphatlrdtavyyciafqgaqklvfgqgtrltinpniqnpdpavyql
rdsdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfacan
afnnsiipedtffp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6u3oH (H:)
mgvsqspsnkvtekgkdvelrcdpisghtalywyrqslgqglefliyfqgnsapdksglp
sdrfsaertggsvstltiqrtqqedsavylcassfralaadtqyfgpgtrltvledlknv
fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeq
palndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
grad

    Sequence, based on observed residues (ATOM records): (download) 
    >6u3oH (H:)
gvsqspsnkvtekgkdvelrcdpisghtalywyrqslgqglefliyfqgnsapdksglps
drfsaertggsvstltiqrtqqedsavylcassfralaadtqyfgpgtrltvledlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
ra

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.