PDB entry 6u2o

View 6u2o on RCSB PDB site
Description: structure of human dna polymerase beta misinserting dampnpp opposite the 5'g of the cisplatin pt-gg intrastrand crosslink
Deposited on 2019-08-20, released 2020-08-26
The last revision was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA (5'-d(p*gp*tp*gp*gp*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'P':
    Compound: DNA (5'-d(*gp*gp*tp*gp*ap*tp*gp*gp*gp*c)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'T':
    Compound: DNA (5'-d(*cp*cp*cp*ap*cp*gp*gp*cp*cp*cp*ap*tp*cp*ap*cp*c)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: MG, NA, DZ4, CPT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6u2oA (A:)
mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
lgvtgvageplpvdsekdifdyiqwkyrepkdrse

    Sequence, based on observed residues (ATOM records):
    >6u2oA (A:)
qetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgt
kiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrk
nedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaes
sgdmdvllthpsftsesqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndeke
yphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvage
plpvdsekdifdyiqwkyrepkdrse

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.