PDB entry 6u16

View 6u16 on RCSB PDB site
Description: human thymine dna glycosylase n140a mutant bound to dna with 5- carboxyl-dc substrate
Deposited on 2019-08-15, released 2019-11-20
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: G/T mismatch-specific thymine DNA glycosylase
    Species: Homo sapiens [TaxId:9606]
    Gene: TDG
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13569
      • engineered mutation (58)
  • Chain 'C':
    Compound: DNA (28-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'D':
    Compound: DNA (28-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: 1CC, CSO, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6u16A (A:)
skksgksakskekqekitdtfkvkrkvdrfngvseaelltktlpdiltfnldiviigiap
glmaaykghhypgpgnhfwkclfmsglsevqlnhmddhtlpgkygigftnmverttpgsk
dlsskefreggrilvqklqkyqpriavfngkciyeifskevfgvkvknlefglqphkipd
tetlcyvmpsssarcaqfpraqdkvhyyiklkdlrdqlkgiernmdv

    Sequence, based on observed residues (ATOM records):
    >6u16A (A:)
vdrfngvseaelltktlpdiltfnldiviigiapglmaaykghhypgpgnhfwkclfmsg
lsevqlnhmddhtlpgkygigftnmverttpgskdlsskefreggrilvqklqkyqpria
vfngkciyeifskevfgvkvknlefglqphkipdtetlcyvmpsssarcaqfpraqdkvh
yyiklkdlrdqlkgiern

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.